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IFNA8: interferon alpha 8

1 protein, 97 patents, 2 drugs, 10 trials, 4,093 NIH grants and 6,880 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIFNA8HGNC
Nameinterferon alpha 8HGNC
NCBI Gene ID3445NCBI Gene
HGNC IDHGNC:5429HGNC
EnsemblENSG00000120242NCBI Gene
AliasesIFN-alphaBNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P32881Interferon alpha-81891Ensembl, GeneID, HGNCUniProt

Patents 97

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4724500 A22026-04-15423P32881Espacenet
EP 4705273 A22026-03-11536P32881Espacenet
EP 4650780 A22025-11-1910280P32881Espacenet
JP 2025169942 A2025-11-141102P32881Espacenet
JP 2025147176 A2025-10-066739P32881Espacenet
JP 2025529142 A2025-09-046657P32881Espacenet
US 12371689 B22025-07-296657P32881Espacenet
JP 2025517970 A2025-06-1210280P32881Espacenet
JP 2025028160 A2025-02-286739P32881Espacenet
JP 2025013347 A2025-01-24536P32881Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RONTALIZUMABCHEMBL1743066Interferon alpha inhibitorINHIBITORChEMBL
SIFALIMUMABCHEMBL1743069Interferon alpha inhibitorINHIBITORChEMBL

Trials 10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01283139SIFALIMUMABPHASE22016-07-11ClinicalTrials.gov
NCT01031836SIFALIMUMABPHASE22018-11-19ClinicalTrials.gov
NCT00979654SIFALIMUMABPHASE22016-08-23ClinicalTrials.gov
NCT00962832RONTALIZUMABPHASE2ClinicalTrials.gov
NCT00657189SIFALIMUMABPHASE2ClinicalTrials.gov
NCT00541749RONTALIZUMABPHASE1ClinicalTrials.gov
NCT00533091SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00482989SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00472758SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00299819SIFALIMUMABPHASE1ClinicalTrials.gov

NIH grants 4093

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success352,025NIH's project files
P30CA008748Cancer Center Support Grant152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award152,025NIH's project files
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis142,025NIH's project files
ZIAAI000647Genes And Gene Products As Immunoadjuvants102,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy92,025NIH's project files
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases92,025NIH's project files
P01AI120943Molecular Mechanisms of Filoviral-host Interactions82,025NIH's project files
R01AI163029Inborn errors of immunity in patients with life-threatening COVID-1982,025NIH's project files
P30AI027763UCSF-Bay Area Center for AIDS Research72,025NIH's project files

Papers 6880

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42728740PubTator, text miningPubMed
42655648PubTator, text miningPubMed
42620100PubTator, text miningPubMed
42607207PubTator, text miningPubMed
42600657PubTator, text miningPubMed
42485309PubTator, text miningPubMed
42480879PubTator, text miningPubMed
42460818PubTator, text miningPubMed
42432708PubTator, text miningPubMed
42374859PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license