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Gene · 345275

HSD17B13: hydroxysteroid 17-beta dehydrogenase 13

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HSD17B13: hydroxysteroid 17-beta dehydrogenase 13. Genes, record 345275. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/345275

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Gene

Symbol
HSD17B13
HGNC
Name
hydroxysteroid 17-beta dehydrogenase 13
HGNC
NCBI Gene ID
345275
NCBI Gene
HGNC ID
HGNC:18685
HGNC
Ensembl
ENSG00000170509
NCBI Gene
Aliases
FLDP, HMFN0376, NIIL497, SCDR9, SDR16C3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q7Z5P417-beta-hydroxysteroid dehydrogenase 133001Ensembl, GeneID, HGNC

Source UniProt

Patents206

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026141239 A2026-07-0211Q7Z5P4Espacenet
JP 2026016717 A2026-02-0321Q7Z5P4Espacenet
EP 4685243 A22026-01-2821Q7Z5P4Espacenet
JP 2026004568 A2026-01-1449552Q7Z5P4Espacenet
EP 4641201 A22025-10-295752Q7Z5P4Espacenet
JP 2025160237 A2025-10-2239Q7Z5P4Espacenet
JP 2025517969 A2025-06-125752Q7Z5P4Espacenet
US 12286677 B22025-04-2921Q7Z5P4Espacenet
KR 1020240148940 A2024-10-1112Q7Z5P4Espacenet
KR 1020240148940 A2024-10-11240Q7Z5P4Espacenet

1 to 10 of 206

See all 206 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,072

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHSD17B13 papersNewest fiscal year
P30DK120515San Diego Digestive Diseases Research Center142025
U01DK061734Clinical Research on Nonalcoholic Fatty Liver Disease142025
U01DK061737Collaborative Clinical Research in Nonalcoholic Steatohepatitis92025
U01DK061738Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)92025
UL1TR001863Yale Clinical and Translational Science Award92025
U01DK061732Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Center-Cleveland site72025
U24DK061730Data Coordinating Center for the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Continuation72025
P30DK120531Pittsburgh Liver Research Center62025
P30ES013508Center of Excellence in Environmental Toxicology62025
P50CA097186The Pacific Northwest Prostate Cancer SPORE62025

1 to 10 of 1,072Source NIH's project files

See all 1,072 nih grants

Papers2,091

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Subtyping metabolic dysfunction-associated steatotic liver disease using electronic health record-linked genomic cohorts reveals diverse etiologies and progression.Nat Commun202642823416PubTator, text miningPubMed
PNPLA3 Is Associated With Hepatocellular Carcinoma, While a Five-Variant Polygenic Risk Score Shows Limited Discrimination in Korean Patients With MASLD.J Gastroenterol Hepatol202642802015PubTator, text miningPubMed
Liver Fibrosis and IRS1 rs2972146 Are Associated With Weight Loss Response After Metabolic Bariatric Surgery.Diabetes Obes Metab202642755140PubTator, text miningPubMed
Risk Factors and Definition of Younger-Onset Metabolic Dysfunction-Associated Steatotic Liver Disease Cirrhosis.Clin Gastroenterol Hepatol202642749101PubTator, text miningPubMed
The urinary tract commensal Peptoniphilus spp. encodes a novel 17β-hydroxysteroid dehydrogenase.Appl Environ Microbiol202642657876PubTator, text miningPubMed
MBOAT7 rs641738 TT genotype is associated with poorer survival in MASLD-related hepatocellular carcinoma.Front Oncol202642656337PubTator, text miningPubMed
Beyond Fat: Reframing MASLD Through Genetics, Clonal Biology, and Precision Hepatology.Pharmaceuticals (Basel)202642653643PubTator, text miningPubMed
Serum Peptidomic Analysis in a Comparative Study of the Efficacy of Benjakul Remedy Versus Loratadine in Allergic Rhinitis Patients.Int J Mol Sci202642653391PubTator, text miningPubMed
High Prevalence of Protective HSD17B13 Variant in Taiwan: An Analysis in Morbidly Obese Individuals and Liver Donors.Genes (Basel)202642650052PubTator, text miningPubMed
The Hsd17b13P260S patient variant knock-in male mouse model provides translational insights into HSD17B13 biology.EBioMedicine202642600259PubTator, text miningPubMed

1 to 10 of 2,091

See all 2,091 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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