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IFNAR1: interferon alpha and beta receptor subunit 1

1 protein, 77 patents, 12 drugs, 1,377 trials, 5,201 NIH grants and 7,487 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIFNAR1HGNC
Nameinterferon alpha and beta receptor subunit 1HGNC
NCBI Gene ID3454NCBI Gene
HGNC IDHGNC:5432HGNC
EnsemblENSG00000142166NCBI Gene
AliasesAVP, CRF2-1, IFN-R-1, IFN-alpha-REC, IFNAR, IFNBR, IFRC, IMD106NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P17181Interferon alpha/beta receptor 15575Ensembl, GeneID, HGNCUniProt

Patents 77

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450032P17181Espacenet
WO 2025247913 A12025-12-041P17181Espacenet
WO 2025247917 A12025-12-041P17181Espacenet
WO 2025247918 A12025-12-041P17181Espacenet
WO 2025247924 A12025-12-041P17181Espacenet
EP 4650780 A22025-11-192728P17181Espacenet
JP 2025147176 A2025-10-066740P17181Espacenet
JP 2025147176 A2025-10-0617017P17181Espacenet
JP 2025529142 A2025-09-042042P17181Espacenet
JP 2025529142 A2025-09-046658P17181Espacenet

Drugs 12

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALBINTERFERON ALFA-2BCHEMBL2107842Interferon alpha/beta receptor agonistAGONISTChEMBL
ANIFROLUMABCHEMBL2364653Interferon-alpha/beta receptor alpha chain antagonistANTAGONISTChEMBL
INTERFERON ALFA-2ACHEMBL2108508Interferon alpha/beta receptor agonistAGONISTChEMBL
INTERFERON ALFA-2BCHEMBL1201558Interferon alpha/beta receptor agonistAGONISTChEMBL
INTERFERON ALFA-N3CHEMBL2109047Interferon alpha/beta receptor agonistAGONISTChEMBL
INTERFERON ALFACON-1CHEMBL1201557Interferon alpha/beta receptor agonistAGONISTChEMBL
INTERFERON BETA-1ACHEMBL1201562Interferon alpha/beta receptor agonistAGONISTChEMBL
INTERFERON BETA-1BCHEMBL1201563Interferon alpha/beta receptor agonistAGONISTChEMBL
PEGINTERFERON ALFA-2ACHEMBL1201560Interferon alpha/beta receptor agonistAGONISTChEMBL
PEGINTERFERON ALFA-2BCHEMBL1201561Interferon alpha/beta receptor agonistAGONISTChEMBL

Trials 1377

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07584083ANIFROLUMABPHASE2ClinicalTrials.gov
NCT07553767INTERFERON ALFA-2BEARLY_PHASE1ClinicalTrials.gov
NCT07537387PEGINTERFERON ALFA-2AClinicalTrials.gov
NCT07521046ROPEGINTERFERON ALFA-2BPHASE1ClinicalTrials.gov
NCT07468916ROPEGINTERFERON ALFA-2BPHASE2ClinicalTrials.gov
NCT07445893INTERFERON ALFA-2BClinicalTrials.gov
NCT07445893PEGINTERFERON ALFA-2BClinicalTrials.gov
NCT07430306ANIFROLUMABPHASE3ClinicalTrials.gov
NCT07330245ANIFROLUMABClinicalTrials.gov
NCT07307586INTERFERON ALFA-2APHASE3ClinicalTrials.gov

NIH grants 5201

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success572,025NIH's project files
P30CA008748Cancer Center Support Grant352,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award292,025NIH's project files
R01AI163029Inborn errors of immunity in patients with life-threatening COVID-19282,025NIH's project files
T32AI007172Infectious Disease/Basic Microbial Pathogenic Mechanisms182,025NIH's project files
P51OD011132Emory National Primate Research Center162,025NIH's project files
ZIAAI001125Virus-Host Interactions: Induction and Evasion of Host Innate Immunity162,025NIH's project files
ZIAAI001265Host factors contributing to susceptibility to COVID-19 disease152,025NIH's project files
ZIAAI001089Viral Hemorrhagic Fevers: Disease Modeling and Transmission142,025NIH's project files
P30CA016672Cancer Center Support Grant132,025NIH's project files

Papers 7487

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818735PubTator, text miningPubMed
42818051PubTator, text miningPubMed
42792593PubTator, text miningPubMed
42782124PubTator, text miningPubMed
42758835PubTator, text miningPubMed
42753295PubTator, text miningPubMed
42746563PubTator, text miningPubMed
42739730PubTator, text miningPubMed
42733068PubTator, text miningPubMed
42723512PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license