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Gene · 3460

IFNGR2: interferon gamma receptor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IFNGR2: interferon gamma receptor 2. Genes, record 3460. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3460

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Gene

Symbol
IFNGR2
HGNC
Name
interferon gamma receptor 2
HGNC
NCBI Gene ID
3460
NCBI Gene
HGNC ID
HGNC:5440
HGNC
Ensembl
ENSG00000159128
NCBI Gene
Aliases
AF-1, IFGR2, IFNGT1, IMD28
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P38484Interferon gamma receptor 23373Ensembl, GeneID, HGNC

Source UniProt

Patents63

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12617829 B22026-05-0589P38484Espacenet
JP 2026004568 A2026-01-1450045P38484Espacenet
EP 4650780 A22025-11-193419P38484Espacenet
EP 4640849 A22025-10-29428P38484Espacenet
EP 4641201 A22025-10-292998P38484Espacenet
EP 4641202 A22025-10-29174P38484Espacenet
EP 4641203 A22025-10-29111P38484Espacenet
JP 2025156512 A2025-10-1489P38484Espacenet
JP 2025147176 A2025-10-0616728P38484Espacenet
JP 2025133877 A2025-09-1189P38484Espacenet

1 to 10 of 63

See all 63 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
INTERFERON GAMMA-1BCHEMBL1201564Interferon gamma receptor agonistAGONIST

Source ChEMBL

Trials86

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06529731INTERFERON GAMMA-1BPHASE2ClinicalTrials.gov
NCT06381661INTERFERON GAMMA-1BPHASE2ClinicalTrials.gov
NCT06222801INTERFERON GAMMA-1BClinicalTrials.gov
NCT06118619INTERFERON GAMMA-1BClinicalTrials.gov
NCT05843786INTERFERON GAMMA-1BPHASE3ClinicalTrials.gov
NCT05653193INTERFERON GAMMA-1BPHASE2ClinicalTrials.gov
NCT05386459INTERFERON GAMMA-1BClinicalTrials.gov
NCT05378646INTERFERON GAMMA-1BPHASE3ClinicalTrials.gov
NCT05359315INTERFERON GAMMA-1BClinicalTrials.gov
NCT05156541INTERFERON GAMMA-1BPHASE3ClinicalTrials.gov

1 to 10 of 86

See all 86 trials

NIH grants1,809

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIFNGR2 papersNewest fiscal year
ZIAAI000647Genes And Gene Products As Immunoadjuvants232025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success202025
P30CA016672Cancer Center Support Grant112025
ZIAAI000646Transgenic Animal Models Of Human Immune Defects112025
ZIAAI001122Studies of Inherited Causes of Fungal Susceptability102025
P30CA046934University of Colorado Cancer Center Support Grant92025
P30ES010126UNC Center for Environmental Health and Susceptibility82025
P30CA008748Cancer Center Support Grant72025
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis72025
ZIACL010304Mutation Analysis Of Selected Lymphoid Immune Disorders62025

1 to 10 of 1,809Source NIH's project files

See all 1,809 nih grants

Papers2,320

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Novel SXXLF Motif in the FXR N-Terminal Domain Mediates Coregulator and Interdomain Interactions.Chembiochem202642723231PubTator, text miningPubMed
Lymph Node Cytology Raising Suspicion for Evolving Secondary Hemophagocytic Lymphohistiocytosis in a Case of Mendelian Susceptibility to Mycobacterial Disease.Diagn Cytopathol202642483808PubTator, text miningPubMed
Extracellular vesicle-encapsulated miRNAs mediate monocyte-endothelial cell crosstalk to exacerbate renal injury in diabetic kidney disease.Int Immunopharmacol202642275918PubTator, text miningPubMed
A novel SXXLF motif in the FXR N-terminal domain mediates coregulator and interdomain interactions.bioRxiv202642239265PubTator, text miningPubMed
Circ_0001185 as a novel therapeutic target for lupus nephritis according to ceRNA network comprehensive analysis.Clin Rheumatol202642026388PubTator, text miningPubMed
Prognostic Stratification and Subtyping of Glioblastoma Using Transient Receptor Potential Channels.Hum Mutat202642016323PubTator, text miningPubMed
Landscape and functional impact of variants of unknown significance of immune response genes in human cancer.Cancer Gene Ther202641935225PubTator, text miningPubMed
Interferon dynamics in deltaretroviruses: why HTLV-1 evades, but BLV responds.Mol Biol Rep202641920397PubTator, text miningPubMed
Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain.Nat Commun202641917044PubTator, text miningPubMed
Emerging roles for the epigenetic modifiers PBRM1 SETD2 and BAP1 in clear cell renal cell carcinoma pathogenesis and prognosis beyond VHL.Discov Oncol202641915349PubTator, text miningPubMed

1 to 10 of 2,320

See all 2,320 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3460

GET https://conductscience.org/api/genes/v1/3460/patents?page=2