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TUBB8: tubulin beta 8 class VIII
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Gene · 347688

Papers278

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 278

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TitleJournalYearPMIDFound bySource
Novel and recurrent TUBB8 variants cause irreversible meiotic spindle defects and refractory ART failure in Chinese women with oocyte maturation arrest.J Assist Reprod Genet202642760497PubTator, text miningPubMed
Spontaneous natural conception and live birth in three patients with likely pathogenic variants in TUBB8, ZP2, and ZP3 associated with female subfertility.J Ovarian Res202642458583PubTator, text miningPubMed
Gene panel analysis for oocyte/zygote/embryo maturation arrest in female infertility: a multicenter study in Japan.Sci Rep202642409946PubTator, text miningPubMed
Deciphering the role of tubulin's C-terminal tail in kinesin binding using computational and clustering approaches.Sci Rep202642168523PubTator, text miningPubMed
Lessons learned from the exome sequencing of nine cases of infertility and the way forward.Reprod Biomed Online202641932285PubTator, text miningPubMed
Genetic Mutations and Non-Genomic Dysregulation in Human Preimplantation Embryo Arrest.Int J Mol Sci202641828362PubTator, text miningPubMed
TUBB8 variants in infertile Japanese women, including a novel homozygous nonsense variant causing zygote multinucleation.Reprod Biomed Online202641762928PubTator, text miningPubMed
Functional Analysis of a Novel Missense Mutation c.1039A > G of TUBB8 in Infertile Women.Biochem Genet202640601103PubTator, text miningPubMed
[Analysis of a case with oocyte maturation disorder caused by a heterozygous c.728C>T (p.P243L) missense variant of TUBB8 gene and literature review].Zhonghua Yi Xue Yi Chuan Xue Za Zhi202541070645PubTator, text miningPubMed
Neurodevelopmental status of children aged 12 to 60 months conceived with artificial oocyte activation in a Cross-Sectional study.Sci Rep202540731130PubTator, text miningPubMed
Molecular Guardians of Oocyte Maturation: A Systematic Review on TUBB8, KIF11, and CKAP5 in IVF Outcomes.Int J Mol Sci202540650169PubTator, text miningPubMed
Genetic landscape of primary ovarian insufficiency in Bangladeshi women through whole exome sequencing.Clin Chim Acta202540505883PubTator, text miningPubMed
Identification of novel variants and expansion of the phenotypic spectrum in PATL2, WEE2, and TUBB8 associated with human early embryonic arrest.J Assist Reprod Genet202540399709PubTator, text miningPubMed
Three Novel Mutations in TUBB8 Cause Female Infertility Due to Multiple Morphological Abnormalities of the Oocyte and Early Embryo.Reprod Sci202540246784PubTator, text miningPubMed
Paired copy number variation analysis in siblings discordant for familial Parkinson's disease.Ann Clin Biochem202540037983PubTator, text miningPubMed
Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibition.Clin Transl Med202539834092PubTator, text miningPubMed
Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan.Elife202439480006PubTator, text miningPubMed
Unraveling the mysteries of early embryonic arrest: genetic factors and molecular mechanisms.J Assist Reprod Genet202439325344PubTator, text miningPubMed
SEPT9: From pan-cancer to lung squamous cell carcinoma.BMC Cancer202439237897PubTator, text miningPubMed
Biallelic variants in α-tubulin isotypes cause female infertility characterised as recurrent preimplantation embryo arrest.J Med Genet202439209701PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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