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IGFBP2: insulin like growth factor binding protein 2

1 protein, 40 patents, 0 drugs, 0 trials, 3,177 NIH grants and 6,477 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIGFBP2HGNC
Nameinsulin like growth factor binding protein 2HGNC
NCBI Gene ID3485NCBI Gene
HGNC IDHGNC:5471HGNC
EnsemblENSG00000115457NCBI Gene
AliasesIBP2, IGF-BP53NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P18065Insulin-like growth factor-binding protein 23251Ensembl, GeneID, HGNCUniProt

Patents 40

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19865P18065Espacenet
EP 4641201 A22025-10-29610P18065Espacenet
JP 2025147176 A2025-10-066787P18065Espacenet
JP 2025529142 A2025-09-046672P18065Espacenet
EP 4606428 A22025-08-2719P18065Espacenet
WO 2025166063 A12025-08-071P18065Espacenet
US 12371689 B22025-07-296672P18065Espacenet
JP 2025517969 A2025-06-12610P18065Espacenet
JP 2025517970 A2025-06-12865P18065Espacenet
WO 2025081160 A12025-04-1752P18065Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3177

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant572,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)92,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE92,025NIH's project files
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer92,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program72,025NIH's project files
P30CA012197Cancer Center Support Grant72,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant72,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA72,025NIH's project files
P30CA016087Cancer Center Support Grant62,025NIH's project files

Papers 6477

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818471PubTator, text miningPubMed
42810422PubTator, text miningPubMed
42809553PubTator, text miningPubMed
42791915PubTator, text miningPubMed
42778924PubTator, text miningPubMed
42741937PubTator, text miningPubMed
42716219PubTator, text miningPubMed
42679336PubTator, text miningPubMed
42667046PubTator, text miningPubMed
42652933PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license