Gene · 3490
IGFBP7: insulin like growth factor binding protein 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IGFBP7: insulin like growth factor binding protein 7. Genes, record 3490. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3490
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16270 | Insulin-like growth factor-binding protein 7 | 282 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents142
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 49926 | Q16270 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3635 | Q16270 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3229 | Q16270 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6804 | Q16270 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6677 | Q16270 | Espacenet |
| EP 4606428 A2 | 2025-08-27 | 42 | Q16270 | Espacenet |
| JP 2025120225 A | 2025-08-15 | 2 | Q16270 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6677 | Q16270 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3229 | Q16270 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3635 | Q16270 | Espacenet |
1 to 10 of 142
See all 142 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,016
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IGFBP7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 15 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 11 | 2025 |
| R01GM110240 | Explainable, Fair, Reproducible and Collaborative Surgical Artificial Intelligence: Integrating data, algorithms and clinical reasoning for surgical risk assessment (XAI-IDEALIST) | 8 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 5 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
| P01AG062413 | Targeting Cellular Senescence to Extend Healthspan | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| R01DK072381 | Kidney Injury Molecule-1 in Epithelial Repair | 4 | 2025 |
| U01DK114923 | Integrated spatial interrogation of cellular and molecular signatures of human kidney disease | 4 | 2025 |
1 to 10 of 2,016Source NIH's project files
See all 2,016 nih grantsPapers3,920
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multicellular Cross Talk and Therapeutic Vaccines in Heart Failure. | Physiology (Bethesda) | 2027 | 42053567 | PubTator, text mining | PubMed |
| PROK1 Expression Is Associated With Prognosis and May Influence Response to Antiandrogen Therapy in Prostate Cancer. | Prostate Cancer | 2026 | 42812728 | PubTator, text mining | PubMed |
| Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques. | Geroscience | 2026 | 42799938 | PubTator, text mining | PubMed |
| Senescence-Associated Checkpoint Gene Dysregulation in Established Osteoarthritis: Integrated Transcriptomic Analysis and In Vitro Evaluation of CDK6 and WEE1. | Biomedicines | 2026 | 42792657 | PubTator, text mining | PubMed |
| Point-of-Care Assessment of Kidney Function in Chronic Kidney Disease: Current Technologies and Future Perspectives. | Med Sci (Basel) | 2026 | 42783394 | PubTator, text mining | PubMed |
| Correlation analysis of Serum NT-pro-BNP, IGFBP-7 and CTRP12 levels in chronic heart failure patients. | J Med Biochem | 2026 | 42781421 | PubTator, text mining | PubMed |
| Serum MIC-1, LMTK-3 and IGFBP-7 levels in the prognosis of lung cancer treated with ablation combined with chemotherapy. | J Med Biochem | 2026 | 42781307 | PubTator, text mining | PubMed |
| The impact of low carbohydrate diet on the plasma proteomic profile of individuals with obesity. | Front Nutr | 2026 | 42780918 | PubTator, text mining | PubMed |
| Early biomarkers of acute kidney injury after lung transplantation. | JHLT Open | 2026 | 42756889 | PubTator, text mining | PubMed |
| Occupational heatstroke-induced acute kidney injury: a narrative review of mechanisms, biomarkers, and the timing of blood purification initiation. | Ren Fail | 2026 | 42734065 | PubTator, text mining | PubMed |
1 to 10 of 3,920
See all 3,920 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3490
GET https://conductscience.org/api/genes/v1/3490/patents?page=2