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Gene · 3490

IGFBP7: insulin like growth factor binding protein 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IGFBP7: insulin like growth factor binding protein 7. Genes, record 3490. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3490

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Gene

Symbol
IGFBP7
HGNC
Name
insulin like growth factor binding protein 7
HGNC
NCBI Gene ID
3490
NCBI Gene
HGNC ID
HGNC:5476
HGNC
Ensembl
ENSG00000163453
NCBI Gene
Aliases
AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16270Insulin-like growth factor-binding protein 72821Ensembl, GeneID, HGNC

Source UniProt

Patents142

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449926Q16270Espacenet
EP 4650780 A22025-11-193635Q16270Espacenet
EP 4641201 A22025-10-293229Q16270Espacenet
JP 2025147176 A2025-10-066804Q16270Espacenet
JP 2025529142 A2025-09-046677Q16270Espacenet
EP 4606428 A22025-08-2742Q16270Espacenet
JP 2025120225 A2025-08-152Q16270Espacenet
US 12371689 B22025-07-296677Q16270Espacenet
JP 2025517969 A2025-06-123229Q16270Espacenet
JP 2025517970 A2025-06-123635Q16270Espacenet

1 to 10 of 142

See all 142 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,016

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIGFBP7 papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
P30CA016672Cancer Center Support Grant112025
UL1TR001863Yale Clinical and Translational Science Award112025
R01GM110240Explainable, Fair, Reproducible and Collaborative Surgical Artificial Intelligence: Integrating data, algorithms and clinical reasoning for surgical risk assessment (XAI-IDEALIST)82025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes52025
P30CA046934University of Colorado Cancer Center Support Grant52025
P01AG062413Targeting Cellular Senescence to Extend Healthspan42025
P30CA015704Cancer Center Support Grant42025
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair42025
U01DK114923Integrated spatial interrogation of cellular and molecular signatures of human kidney disease42025

1 to 10 of 2,016Source NIH's project files

See all 2,016 nih grants

Papers3,920

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multicellular Cross Talk and Therapeutic Vaccines in Heart Failure.Physiology (Bethesda)202742053567PubTator, text miningPubMed
PROK1 Expression Is Associated With Prognosis and May Influence Response to Antiandrogen Therapy in Prostate Cancer.Prostate Cancer202642812728PubTator, text miningPubMed
Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques.Geroscience202642799938PubTator, text miningPubMed
Senescence-Associated Checkpoint Gene Dysregulation in Established Osteoarthritis: Integrated Transcriptomic Analysis and In Vitro Evaluation of CDK6 and WEE1.Biomedicines202642792657PubTator, text miningPubMed
Point-of-Care Assessment of Kidney Function in Chronic Kidney Disease: Current Technologies and Future Perspectives.Med Sci (Basel)202642783394PubTator, text miningPubMed
Correlation analysis of Serum NT-pro-BNP, IGFBP-7 and CTRP12 levels in chronic heart failure patients.J Med Biochem202642781421PubTator, text miningPubMed
Serum MIC-1, LMTK-3 and IGFBP-7 levels in the prognosis of lung cancer treated with ablation combined with chemotherapy.J Med Biochem202642781307PubTator, text miningPubMed
The impact of low carbohydrate diet on the plasma proteomic profile of individuals with obesity.Front Nutr202642780918PubTator, text miningPubMed
Early biomarkers of acute kidney injury after lung transplantation.JHLT Open202642756889PubTator, text miningPubMed
Occupational heatstroke-induced acute kidney injury: a narrative review of mechanisms, biomarkers, and the timing of blood purification initiation.Ren Fail202642734065PubTator, text miningPubMed

1 to 10 of 3,920

See all 3,920 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3490

GET https://conductscience.org/api/genes/v1/3490/patents?page=2