Gene · 3512
JCHAIN: joining chain of multimeric IgA and IgM
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. JCHAIN: joining chain of multimeric IgA and IgM. Genes, record 3512. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3512
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P01591 | Immunoglobulin J chain | 159 | 31 | Ensembl, GeneID, HGNC |
Source UniProt
Patents247
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026220355 A1 | 2026-10-22 | 272 | P01591 | Espacenet |
| WO 2026215253 A1 | 2026-10-15 | 26 | P01591 | Espacenet |
| WO 2026215274 A1 | 2026-10-15 | 23 | P01591 | Espacenet |
| EP 4801965 A1 | 2026-09-09 | 148 | P01591 | Espacenet |
| EP 4791787 A2 | 2026-08-19 | 6174 | P01591 | Espacenet |
| EP 4791787 A2 | 2026-08-19 | 76 | P01591 | Espacenet |
| US 12649791 B2 | 2026-06-09 | 1 | P01591 | Espacenet |
| JP 2026517755 A | 2026-06-02 | 76 | P01591 | Espacenet |
| EP 4727978 A2 | 2026-04-22 | 90 | P01591 | Espacenet |
| EP 4724500 A2 | 2026-04-15 | 1076 | P01591 | Espacenet |
1 to 10 of 247
See all 247 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,049
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | JCHAIN papers | Newest fiscal year |
|---|---|---|---|
| P30AG017265 | USC/UCLA Center on Biodemography and Population Health | 12 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P42ES004911 | Environmental, Microbial and Mammalian Biomolecular Responses to AhR Ligands | 5 | 2025 |
| UL1TR002345 | Washington University Institute of Clinical and Translational Sciences | 5 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 3 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 3 | 2025 |
1 to 10 of 1,049Source NIH's project files
See all 1,049 nih grantsPapers1,526
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Clonotypic characterization defines B-cell drivers of clonal expansion and intratumor heterogeneity in IgM monoclonal gammopathies. | Hemasphere | 2026 | 42732362 | PubTator, text mining | PubMed |
| Association of Th2-like inflammation with Tfh/Tph-germinal center immune programmes in submandibular gland lesions of IgG4-related disease. | Rheumatology (Oxford) | 2026 | 42538826 | PubTator, text mining | PubMed |
| Prognosis and Immunotherapy Effect of Triple-Negative Breast Cancer by Lactylation-Related Genes and Experimental Validation. | Oncol Res | 2026 | 42358833 | PubTator, text mining | PubMed |
| Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation. | Extracell Vesicle | 2026 | 42344609 | PubTator, text mining | PubMed |
| The paradox of action: Trajectories in distress, meaning, and gene regulation following self-directed activist engagement among Black women. | SSM Ment Health | 2026 | 42312185 | PubTator, text mining | PubMed |
| Identification and validation of a seven-gene metastasis-associated prognostic model in breast cancer. | Front Genet | 2026 | 42186460 | PubTator, text mining | PubMed |
| Mediterranean diet adherence is associated with antiviral, neuroimmune, and cardiometabolic proteomic profiles in people with HIV. | Front Nutr | 2026 | 42099764 | PubTator, text mining | PubMed |
| Targeted immune response gene expression profiles linked with necrosis and mortality in preterm infants with surgical necrotizing enterocolitis. | World J Pediatr Surg | 2026 | 41919181 | PubTator, text mining | PubMed |
| A Novel Prognostic Signature Composed of Autophagy and Liver Metastasis in Colorectal Cancer: Comprehensive Analysis of Bulk and Single-Cell Transcriptomic Data. | Immunotargets Ther | 2026 | 41918766 | PubTator, text mining | PubMed |
| Glycolytic reprogramming mediated by the ADAM12/IGF1 axis promotes ossification of the posterior longitudinal ligament. | Cell Death Discov | 2026 | 41881952 | PubTator, text mining | PubMed |
1 to 10 of 1,526
See all 1,526 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3512
GET https://conductscience.org/api/genes/v1/3512/patents?page=2