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Gene · 3512

JCHAIN: joining chain of multimeric IgA and IgM

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. JCHAIN: joining chain of multimeric IgA and IgM. Genes, record 3512. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3512

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Gene

Symbol
JCHAIN
HGNC
Name
joining chain of multimeric IgA and IgM
HGNC
NCBI Gene ID
3512
NCBI Gene
HGNC ID
HGNC:5713
HGNC
Ensembl
ENSG00000132465
NCBI Gene
Aliases
IGCJ, IGJ, JCH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P01591Immunoglobulin J chain15931Ensembl, GeneID, HGNC

Source UniProt

Patents247

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026220355 A12026-10-22272P01591Espacenet
WO 2026215253 A12026-10-1526P01591Espacenet
WO 2026215274 A12026-10-1523P01591Espacenet
EP 4801965 A12026-09-09148P01591Espacenet
EP 4791787 A22026-08-196174P01591Espacenet
EP 4791787 A22026-08-1976P01591Espacenet
US 12649791 B22026-06-091P01591Espacenet
JP 2026517755 A2026-06-0276P01591Espacenet
EP 4727978 A22026-04-2290P01591Espacenet
EP 4724500 A22026-04-151076P01591Espacenet

1 to 10 of 247

See all 247 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,049

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleJCHAIN papersNewest fiscal year
P30AG017265USC/UCLA Center on Biodemography and Population Health122025
P30CA016672Cancer Center Support Grant82025
P42ES004911Environmental, Microbial and Mammalian Biomolecular Responses to AhR Ligands52025
UL1TR002345Washington University Institute of Clinical and Translational Sciences52025
P30CA091842Cancer Center Support Grant42025
P30CA008748Cancer Center Support Grant32025
P30CA013696Cancer Center Support Grant32025
P30CA016042Cancer Center Support Grant32025
P30CA016087Cancer Center Support Grant32025
P30CA034196Cancer Center Support (CORE) Grant32025

1 to 10 of 1,049Source NIH's project files

See all 1,049 nih grants

Papers1,526

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clonotypic characterization defines B-cell drivers of clonal expansion and intratumor heterogeneity in IgM monoclonal gammopathies.Hemasphere202642732362PubTator, text miningPubMed
Association of Th2-like inflammation with Tfh/Tph-germinal center immune programmes in submandibular gland lesions of IgG4-related disease.Rheumatology (Oxford)202642538826PubTator, text miningPubMed
Prognosis and Immunotherapy Effect of Triple-Negative Breast Cancer by Lactylation-Related Genes and Experimental Validation.Oncol Res202642358833PubTator, text miningPubMed
Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation.Extracell Vesicle202642344609PubTator, text miningPubMed
The paradox of action: Trajectories in distress, meaning, and gene regulation following self-directed activist engagement among Black women.SSM Ment Health202642312185PubTator, text miningPubMed
Identification and validation of a seven-gene metastasis-associated prognostic model in breast cancer.Front Genet202642186460PubTator, text miningPubMed
Mediterranean diet adherence is associated with antiviral, neuroimmune, and cardiometabolic proteomic profiles in people with HIV.Front Nutr202642099764PubTator, text miningPubMed
Targeted immune response gene expression profiles linked with necrosis and mortality in preterm infants with surgical necrotizing enterocolitis.World J Pediatr Surg202641919181PubTator, text miningPubMed
A Novel Prognostic Signature Composed of Autophagy and Liver Metastasis in Colorectal Cancer: Comprehensive Analysis of Bulk and Single-Cell Transcriptomic Data.Immunotargets Ther202641918766PubTator, text miningPubMed
Glycolytic reprogramming mediated by the ADAM12/IGF1 axis promotes ossification of the posterior longitudinal ligament.Cell Death Discov202641881952PubTator, text miningPubMed

1 to 10 of 1,526

See all 1,526 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3512

GET https://conductscience.org/api/genes/v1/3512/patents?page=2