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Gene · 353

APRT: adenine phosphoribosyltransferase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. APRT: adenine phosphoribosyltransferase. Genes, record 353. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/353

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Gene

Symbol
APRT
HGNC
Name
adenine phosphoribosyltransferase
HGNC
NCBI Gene ID
353
NCBI Gene
HGNC ID
HGNC:626
HGNC
Ensembl
ENSG00000198931
NCBI Gene
Aliases
AMP, APRTD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07741Adenine phosphoribosyltransferase18016Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436606P07741Espacenet
EP 4650780 A22025-11-1910037P07741Espacenet
JP 2025517970 A2025-06-1210037P07741Espacenet
JP 2025062604 A2025-04-142638P07741Espacenet
US 11446398 B22022-09-202638P07741Espacenet
JP 2022524081 A2022-04-27105609P07741Espacenet
US 11078247 B22021-08-03673P07741Espacenet
WO 2020043864 A12020-03-05180P07741Espacenet
JP 2019054813 A2019-04-11217041P07741Espacenet
US 9952224 B22018-04-24274P07741Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,685

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAPRT papersNewest fiscal year
P30CA008748Cancer Center Support Grant192025
P30CA016672Cancer Center Support Grant92025
P30CA138292Winship Cancer Institute Cancer Center Support Grant62025
P30CA016058Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025
R01CA093729Repair of Genome Destabilizing DNA Structures52025
U24HG006834Broad-Geisinger Clinical Genome Resource52025
ZIAHG200359Genomic Ascertainment - Molecular and Genetic Aspects52025
P30CA091842Cancer Center Support Grant42025
P30ES010126UNC Center for Environmental Health and Susceptibility42025

1 to 10 of 1,685Source NIH's project files

See all 1,685 nih grants

Papers3,627

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple-negative breast cancer.J Pathol202642713707PubTator, text miningPubMed
Autophagy in ischemic stroke: pathophysiology, therapeutics, and challenges ahead.Front Stroke202642548587PubTator, text miningPubMed
Whole-exome sequencing identifies rare genetic variants in Egyptian patients with hypertrophic cardiomyopathy: a pilot study.Cardiol Young202642478525PubTator, text miningPubMed
Genetic Determinants of Telomere Length and Their Role in Human Disease: Molecular Mechanisms and Underrepresented Populations' Perspectives.Biomedicines202642351635PubTator, text miningPubMed
Vitamin D-AMP axis in host defense against fungal infections.Front Nutr202642325508PubTator, text miningPubMed
The landscape of MET alterations in non-small cell lung cancer in Southeastern China: a real-world study.BMC Cancer202642185795PubTator, text miningPubMed
Chronic psychological stress potentiates IgE class switch recombination via glucocorticoid receptor-mediated epigenetic reprogramming of B cells.Brain Behav Immun202642119910PubTator, text miningPubMed
Comparative sequence, structural, and phylogenetic analyses provide insights into the salinity-associated evolution of antimicrobial peptides in teleosts.Comp Biochem Physiol A Mol Integr Physiol202642097276PubTator, text miningPubMed
Patch type nucleotide sequence identities between genomes from many different species facilitate illegitimate recombination.Sci Rep202641905996PubTator, text miningPubMed
Molecular identification, characterization and antibacterial activity of fungal-mediated silver nanoparticles against Bacillus subtilis sh3 and Klebsiella pneumoniae sh4.Sci Rep202641904189PubTator, text miningPubMed

1 to 10 of 3,627

See all 3,627 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/353

GET https://conductscience.org/api/genes/v1/353/patents?page=2