Gene · 353
APRT: adenine phosphoribosyltransferase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. APRT: adenine phosphoribosyltransferase. Genes, record 353. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/353
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07741 | Adenine phosphoribosyltransferase | 180 | 16 | Ensembl, GeneID, HGNC |
Source UniProt
Patents27
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36606 | P07741 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10037 | P07741 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10037 | P07741 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 2638 | P07741 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 2638 | P07741 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 105609 | P07741 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 673 | P07741 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 180 | P07741 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 217041 | P07741 | Espacenet |
| US 9952224 B2 | 2018-04-24 | 274 | P07741 | Espacenet |
1 to 10 of 27
See all 27 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,685
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | APRT papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 19 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30CA138292 | Winship Cancer Institute Cancer Center Support Grant | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| R01CA093729 | Repair of Genome Destabilizing DNA Structures | 5 | 2025 |
| U24HG006834 | Broad-Geisinger Clinical Genome Resource | 5 | 2025 |
| ZIAHG200359 | Genomic Ascertainment - Molecular and Genetic Aspects | 5 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 4 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 4 | 2025 |
1 to 10 of 1,685Source NIH's project files
See all 1,685 nih grantsPapers3,627
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple-negative breast cancer. | J Pathol | 2026 | 42713707 | PubTator, text mining | PubMed |
| Autophagy in ischemic stroke: pathophysiology, therapeutics, and challenges ahead. | Front Stroke | 2026 | 42548587 | PubTator, text mining | PubMed |
| Whole-exome sequencing identifies rare genetic variants in Egyptian patients with hypertrophic cardiomyopathy: a pilot study. | Cardiol Young | 2026 | 42478525 | PubTator, text mining | PubMed |
| Genetic Determinants of Telomere Length and Their Role in Human Disease: Molecular Mechanisms and Underrepresented Populations' Perspectives. | Biomedicines | 2026 | 42351635 | PubTator, text mining | PubMed |
| Vitamin D-AMP axis in host defense against fungal infections. | Front Nutr | 2026 | 42325508 | PubTator, text mining | PubMed |
| The landscape of MET alterations in non-small cell lung cancer in Southeastern China: a real-world study. | BMC Cancer | 2026 | 42185795 | PubTator, text mining | PubMed |
| Chronic psychological stress potentiates IgE class switch recombination via glucocorticoid receptor-mediated epigenetic reprogramming of B cells. | Brain Behav Immun | 2026 | 42119910 | PubTator, text mining | PubMed |
| Comparative sequence, structural, and phylogenetic analyses provide insights into the salinity-associated evolution of antimicrobial peptides in teleosts. | Comp Biochem Physiol A Mol Integr Physiol | 2026 | 42097276 | PubTator, text mining | PubMed |
| Patch type nucleotide sequence identities between genomes from many different species facilitate illegitimate recombination. | Sci Rep | 2026 | 41905996 | PubTator, text mining | PubMed |
| Molecular identification, characterization and antibacterial activity of fungal-mediated silver nanoparticles against Bacillus subtilis sh3 and Klebsiella pneumoniae sh4. | Sci Rep | 2026 | 41904189 | PubTator, text mining | PubMed |
1 to 10 of 3,627
See all 3,627 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/353
GET https://conductscience.org/api/genes/v1/353/patents?page=2