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KLK3: kallikrein related peptidase 3

1 protein, 337 patents, 1 drug, 0 trials, 9,390 NIH grants and 56,437 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolKLK3HGNC
Namekallikrein related peptidase 3HGNC
NCBI Gene ID354NCBI Gene
HGNC IDHGNC:6364HGNC
EnsemblENSG00000142515NCBI Gene
AliasesAPS, KLK2A1, PSA, hK3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07288Prostate-specific antigen2616Ensembl, GeneID, HGNCUniProt

Patents 337

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026012855 A2026-01-2717P07288Espacenet
JP 2026004568 A2026-01-1450561P07288Espacenet
EP 4650780 A22025-11-194943P07288Espacenet
EP 4640849 A22025-10-29685P07288Espacenet
EP 4641201 A22025-10-294521P07288Espacenet
JP 2025147176 A2025-10-067546P07288Espacenet
JP 2025529142 A2025-09-046827P07288Espacenet
US 12371689 B22025-07-296827P07288Espacenet
JP 2025519096 A2025-06-24685P07288Espacenet
JP 2025517969 A2025-06-124521P07288Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CAPROMABCHEMBL2108285Prostate specific antigen binding agentBINDING AGENTChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 9390

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant6542,025NIH's project files
P50CA092629SPORE in Prostate Cancer3682,025NIH's project files
P30CA006973Regional Oncology Research Center3242,025NIH's project files
P30CA016672Cancer Center Support Grant2692,025NIH's project files
P50CA097186The Pacific Northwest Prostate Cancer SPORE2202,025NIH's project files
ZIABC010655Prostate Cancer Imaging1122,025NIH's project files
ZIACL040015Interventional Oncology872,025NIH's project files
ZIABC011081Prostate Section862,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant852,025NIH's project files
P50CA186786Michigan Prostate SPORE 2025-2030792,025NIH's project files

Papers 56437

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823706PubTator, text miningPubMed
42823219PubTator, text miningPubMed
42820647PubTator, text miningPubMed
42817243PubTator, text miningPubMed
42814916PubTator, text miningPubMed
42813874PubTator, text miningPubMed
42810248PubTator, text miningPubMed
42809793PubTator, text miningPubMed
42808408PubTator, text miningPubMed
42808395PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license