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Gene · 3549

IHH: Indian hedgehog signaling molecule

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IHH: Indian hedgehog signaling molecule. Genes, record 3549. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3549

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Gene

Symbol
IHH
HGNC
Name
Indian hedgehog signaling molecule
HGNC
NCBI Gene ID
3549
NCBI Gene
HGNC ID
HGNC:5956
HGNC
Ensembl
ENSG00000163501
NCBI Gene
Aliases
BDA1, HHG2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14623Indian hedgehog protein4118Ensembl, GeneID, HGNC

Source UniProt

Patents77

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449730Q14623Espacenet
EP 4650780 A22025-11-193642Q14623Espacenet
JP 2025147176 A2025-10-066847Q14623Espacenet
JP 2025529142 A2025-09-046691Q14623Espacenet
US 12371689 B22025-07-296691Q14623Espacenet
JP 2025517970 A2025-06-123642Q14623Espacenet
JP 2025028160 A2025-02-286847Q14623Espacenet
KR 1020250010750 A2025-01-216847Q14623Espacenet
US 12121530 B22024-10-22107Q14623Espacenet
JP 2024109657 A2024-08-146854Q14623Espacenet

1 to 10 of 77

See all 77 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,031

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIHH papersNewest fiscal year
P30CA008748Cancer Center Support Grant162025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202872025
R01AA010154TNF alpha and Recovery from Alcoholic Liver Injury72025
ZIAHD000640Regulation Of Childhood Growth72025
P30AR069619Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)62025
P30CA016672Cancer Center Support Grant62025
P30DK063491Diabetes Research Center (DRC)62025
R01DK075787Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum62025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant52025
ZIAES103311Environmental Signaling in Reproduction and Pregnancy52025

1 to 10 of 2,031Source NIH's project files

See all 2,031 nih grants

Papers2,936

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Idiopathic short stature in the genomic era: a focused narrative review of genotype-phenotype correlation, selective neuroimaging, IGF-1 biology, and growth hormone responsiveness.Clin Pediatr Endocrinol202642824949PubTator, text miningPubMed
Spatial multi-omics decoding of the fracture nonunion niche: from immune-vascular-skeletal crosstalk to precision regeneration.Front Med (Lausanne)202642761428PubTator, text miningPubMed
From FGFR3 Hyperactivation to Disease-Modifying Therapy in Pediatric Achondroplasia: Molecular Mechanisms, Clinical Evidence, and Emerging Treatments.Children (Basel)202642650460PubTator, text miningPubMed
Growth Plate Morphogens as Potential Modulators of Cellular Tissue Remodeling by Annulus Fibrosus Cells.JOR Spine202642633138PubTator, text miningPubMed
Articular Cartilage Tissue Engineering: Cells, Bioinstructive Scaffolds, Immunological Microenvironment, and Emerging Technologies.Bioengineering (Basel)202642510461PubTator, text miningPubMed
Inherent tissue homeostasis of the juvenile metaphysis provides a foundation for osteosarcoma development.Nat Commun202642363015PubTator, text miningPubMed
Mechanobiology of hypertrophic chondrocyte mineralization: Biomechanical regulation and therapeutic implications in skeletal disorders.Mechanobiol Med202642317771PubTator, text miningPubMed
Molecular signature of human endometrial stem/progenitor cells at the single-cell level.Stem Cell Reports202642276064PubTator, text miningPubMed
CDs-PEI/siIhh Delivery System for the Treatment of Osteoarthritis.ACS Appl Bio Mater202642187059PubTator, text miningPubMed
Construction of pre-vascularized bone-like tissue by incorporation of mesodermal progenitor cells through simulating endochondral ossification.Stem Cell Res Ther202642178573PubTator, text miningPubMed

1 to 10 of 2,936

See all 2,936 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3549

GET https://conductscience.org/api/genes/v1/3549/patents?page=2