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IL3RA: interleukin 3 receptor subunit alpha

1 protein, 229 patents, 10 drugs, 40 trials, 4,509 NIH grants and 8,508 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL3RAHGNC
Nameinterleukin 3 receptor subunit alphaHGNC
NCBI Gene ID3563NCBI Gene
HGNC IDHGNC:6012HGNC
EnsemblENSG00000185291, ENSG00000292332NCBI Gene
AliasesCD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3RaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P26951Interleukin-3 receptor subunit alpha3784Ensembl, GeneID, HGNCUniProt

Patents 229

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4777551 A12026-07-2211P26951Espacenet
JP 2026086801 A2026-05-2636P26951Espacenet
EP 4705273 A22026-03-11307P26951Espacenet
JP 2026009121 A2026-01-1957P26951Espacenet
WO 2026013158 A12026-01-15401P26951Espacenet
JP 2026004568 A2026-01-1450236P26951Espacenet
EP 4650780 A22025-11-195748P26951Espacenet
EP 4641201 A22025-10-295405P26951Espacenet
EP 4633648 A12025-10-2237P26951Espacenet
US 12441798 B22025-10-14206P26951Espacenet

Drugs 10

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CSL-360CHEMBL2109327Interleukin-3 receptor subunit alpha inhibitorINHIBITORChEMBL
CSL-360CHEMBL2109327Interleukin-3 receptor subunit alpha inhibitorINHIBITORChEMBL
FLOTETUZUMABCHEMBL3990038Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
FLOTETUZUMABCHEMBL3990038Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
PIVEKIMAB SUNIRINECHEMBL4297991Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
PIVEKIMAB SUNIRINECHEMBL4297991Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
TAGRAXOFUSPCHEMBL4297573Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
TAGRAXOFUSPCHEMBL4297573Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
TALACOTUZUMABCHEMBL4297837Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL
TALACOTUZUMABCHEMBL4297837Interleukin-3 receptor subunit alpha binding agentBINDING AGENTChEMBL

Trials 40

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07581002PIVEKIMAB SUNIRINEPHASE2/PHASE3ClinicalTrials.gov
NCT07306832PIVEKIMAB SUNIRINEPHASE1ClinicalTrials.gov
NCT07148180TAGRAXOFUSPPHASE1/PHASE2ClinicalTrials.gov
NCT07007052TAGRAXOFUSPPHASE2ClinicalTrials.gov
NCT06561152TAGRAXOFUSPPHASE1/PHASE2ClinicalTrials.gov
NCT06498973TAGRAXOFUSPPHASE1ClinicalTrials.gov
NCT06456463TAGRAXOFUSPPHASE2ClinicalTrials.gov
NCT06414681TAGRAXOFUSPEARLY_PHASE1ClinicalTrials.gov
NCT06034470PIVEKIMAB SUNIRINEPHASE1ClinicalTrials.gov
NCT05720988TAGRAXOFUSPPHASE1ClinicalTrials.gov

NIH grants 4509

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1032,025NIH's project files
P30CA008748Cancer Center Support Grant672,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro272,025NIH's project files
P51OD011132Emory National Primate Research Center232,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)202,025NIH's project files
P51OD011092Support for National Primate Research Center182,025NIH's project files
P51OD011104Tulane National Primate Research Center182,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant172,025NIH's project files
ZIABC010301Development of Recombinant Toxins to Treat Hematologic Malignancies172,025NIH's project files
T32AI007290Molecular and Cellular Immunobiology162,025NIH's project files

Papers 8508

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42816252PubTator, text miningPubMed
42815783PubTator, text miningPubMed
42809184PubTator, text miningPubMed
42795003PubTator, text miningPubMed
42779343PubTator, text miningPubMed
42764087PubTator, text miningPubMed
42762392PubTator, text miningPubMed
42760567PubTator, text miningPubMed
42760285PubTator, text miningPubMed
42755912PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license