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IL4: interleukin 4

1 protein, 400 patents, 2 drugs, 5 trials, 27,546 NIH grants and 101,232 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL4HGNC
Nameinterleukin 4HGNC
NCBI Gene ID3565NCBI Gene
HGNC IDHGNC:6014HGNC
EnsemblENSG00000113520NCBI Gene
AliasesBCGF-1, BCGF1, BSF-1, BSF1, IL-4, MGC79402NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05112Interleukin-415329Ensembl, GeneID, HGNCUniProt

Patents 400

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4820057 A12026-10-14286P05112Espacenet
EP 4795154 A12026-08-26130P05112Espacenet
WO 2026167214 A12026-08-13135P05112Espacenet
JP 2026086743 A2026-05-26121P05112Espacenet
US 12636346 B22026-05-2614P05112Espacenet
JP 2026513839 A2026-05-01121P05112Espacenet
JP 2026514049 A2026-05-01121P05112Espacenet
EP 4705273 A22026-03-11268P05112Espacenet
EP 4705273 A22026-03-11286P05112Espacenet
US 12559530 B22026-02-24374P05112Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
PASCOLIZUMABCHEMBL2108119Interleukin-4 inhibitorINHIBITORChEMBL
ROMILKIMABCHEMBL4298097Interleukin-4 inhibitorINHIBITORChEMBL

Trials 5

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02921971ROMILKIMABPHASE22022-02-02ClinicalTrials.gov
NCT02345070ROMILKIMABPHASE22020-05-26ClinicalTrials.gov
NCT01638520PASCOLIZUMABPHASE2ClinicalTrials.gov
NCT01529853ROMILKIMABPHASE1/PHASE2ClinicalTrials.gov
NCT00024544PASCOLIZUMABPHASE2ClinicalTrials.gov

NIH grants 27546

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1782,025NIH's project files
P30CA008748Cancer Center Support Grant1542,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award1192,025NIH's project files
P30CA047904Cancer Center Support Grant712,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease662,025NIH's project files
U19AI070235Epithelial Genes in Allergic Inflammation642,025NIH's project files
P30CA016042Cancer Center Support Grant592,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program582,025NIH's project files
P51OD011132Emory National Primate Research Center582,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)542,025NIH's project files

Papers 101232

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827467PubTator, text miningPubMed
42826153PubTator, text miningPubMed
42825488PubTator, text miningPubMed
42823180PubTator, text miningPubMed
42823151PubTator, text miningPubMed
42822860PubTator, text miningPubMed
42818232PubTator, text miningPubMed
42816943PubTator, text miningPubMed
42816545PubTator, text miningPubMed
42815594PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license