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Library / Genes

IL5: interleukin 5

1 protein, 222 patents, 3 drugs, 117 trials, 12,521 NIH grants and 38,321 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL5HGNC
Nameinterleukin 5HGNC
NCBI Gene ID3567NCBI Gene
HGNC IDHGNC:6016HGNC
EnsemblENSG00000113525NCBI Gene
AliasesEDF, IL-5, TRFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05113Interleukin-51345Ensembl, GeneID, HGNCUniProt

Patents 222

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086743 A2026-05-26133P05113Espacenet
EP 4705273 A22026-03-11281P05113Espacenet
EP 4650780 A22025-11-19805P05113Espacenet
US 12473363 B22025-11-18896P05113Espacenet
EP 4641203 A22025-10-2928P05113Espacenet
JP 2025147176 A2025-10-067105P05113Espacenet
JP 2025147176 A2025-10-0616758P05113Espacenet
JP 2025529142 A2025-09-046740P05113Espacenet
WO 2025177214 A12025-08-2828P05113Espacenet
US 12371689 B22025-07-296740P05113Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DEPEMOKIMABCHEMBL4650469Interleukin-5 inhibitorINHIBITORChEMBL
MEPOLIZUMABCHEMBL2108429Interleukin-5 inhibitorINHIBITORChEMBL
RESLIZUMABCHEMBL2107884Interleukin-5 inhibitorINHIBITORChEMBL

Trials 117

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07592104MEPOLIZUMABClinicalTrials.gov
NCT07591753MEPOLIZUMABClinicalTrials.gov
NCT07456033DEPEMOKIMABPHASE3ClinicalTrials.gov
NCT06979323DEPEMOKIMABPHASE3ClinicalTrials.gov
NCT06961214DEPEMOKIMABPHASE3ClinicalTrials.gov
NCT06959095DEPEMOKIMABPHASE3ClinicalTrials.gov
NCT06617754MEPOLIZUMABClinicalTrials.gov
NCT06572267MEPOLIZUMABPHASE2ClinicalTrials.gov
NCT06501807MEPOLIZUMABClinicalTrials.gov
NCT06456450MEPOLIZUMABClinicalTrials.gov

NIH grants 12521

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease612,025NIH's project files
P30CA008748Cancer Center Support Grant582,025NIH's project files
U19AI070235Epithelial Genes in Allergic Inflammation572,025NIH's project files
P30CA016672Cancer Center Support Grant532,025NIH's project files
ZIAAI001130Eosinophils and Eosinophil Activation in the Pathogenesis of Human Disease462,025NIH's project files
U19AI070535Airway Inflammation and Airway Remodeling in Severe Asthma452,025NIH's project files
U19AI095227Viral and Host Determinants of Infant and Childhood Allergy and Asthma422,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award422,025NIH's project files
ZIAAI001065India International Center for Excellence in Research372,025NIH's project files
P51OD011104Tulane National Primate Research Center332,025NIH's project files

Papers 38321

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825488PubTator, text miningPubMed
42825053PubTator, text miningPubMed
42821054PubTator, text miningPubMed
42814219PubTator, text miningPubMed
42809620PubTator, text miningPubMed
42808045PubTator, text miningPubMed
42806728PubTator, text miningPubMed
42805313PubTator, text miningPubMed
42803566PubTator, text miningPubMed
42802784PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license