ConductScience.org, home

Gene · 3587

IL10RA: interleukin 10 receptor subunit alpha

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. IL10RA: interleukin 10 receptor subunit alpha. Genes, record 3587. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3587

On this page

Gene

Symbol
IL10RA
HGNC
Name
interleukin 10 receptor subunit alpha
HGNC
NCBI Gene ID
3587
NCBI Gene
HGNC ID
HGNC:5964
HGNC
Ensembl
ENSG00000110324
NCBI Gene
Aliases
CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13651Interleukin-10 receptor subunit alpha5787Ensembl, GeneID, HGNC

Source UniProt

Patents83

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11304Q13651Espacenet
EP 4688842 A12026-02-1164Q13651Espacenet
US 12528850 B22026-01-2052Q13651Espacenet
JP 2026004568 A2026-01-1450149Q13651Espacenet
EP 4653459 A12025-11-261Q13651Espacenet
EP 4650780 A22025-11-19690Q13651Espacenet
EP 4641201 A22025-10-29484Q13651Espacenet
EP 4641202 A22025-10-2927Q13651Espacenet
EP 4641203 A22025-10-2921Q13651Espacenet
EP 4633648 A12025-10-2227Q13651Espacenet

1 to 10 of 83

See all 83 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
PEGILODECAKINCHEMBL3989992IL-10 receptor agonistAGONIST

Source ChEMBL

Trials5

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03554434PEGILODECAKINClinicalTrials.gov
NCT03382912PEGILODECAKINPHASE22020-09-11ClinicalTrials.gov
NCT03382899PEGILODECAKINPHASE22021-01-20ClinicalTrials.gov
NCT02923921PEGILODECAKINPHASE32020-10-19ClinicalTrials.gov
NCT02009449PEGILODECAKINPHASE1ClinicalTrials.gov

NIH grants2,537

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIL10RA papersNewest fiscal year
P30DK034854Integrated Epithelial and Muscosal Biology222025
P30CA008748Cancer Center Support Grant102025
P30CA016672Cancer Center Support Grant92025
R01AI044938Inhibition of STAT3 and inflammatory cytokine production82025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease72025
P51OD011107California National Primate Research Center72025
R01AI046712Activation of Macrophages in Human Autoimmune Diseases72025
R01AR046713Cytokine regulation of RA synoviocyte phenotype72025
RC2DK118640COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepository72025
R01AR050401Cytokine Balance in Rheumatoid Arthritis62025

1 to 10 of 2,537Source NIH's project files

See all 2,537 nih grants

Papers3,503

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of genetic variants associated with monogenic autoinflammatory diseases in patients with Still's disease using next-generation sequencing.Immunol Res202642821198PubTator, text miningPubMed
Targeting Mcl-1 to restore IL-10-driven Breg suppression reverses allergic asthma.Immunol Lett202642810527PubTator, text miningPubMed
In silico transcriptomic analysis nominates TSPAN32 as a central node of SCFA-driven immunometabolic reprogramming in intestinal epithelial cells.Front Bioinform202642774375PubTator, text miningPubMed
Clinical characteristics and prognosis of infant onset inflammatory bowel disease in Chinese children: a 10-year single-center experience.Transl Pediatr202642724325PubTator, text miningPubMed
Inflammatory Serum Olink Proteomics in Cancer-Related Pain Treated with Opioids: A Pilot Cross-Sectional and Longitudinal Study.J Proteome Res202642695881PubTator, text miningPubMed
Bioinformatics analysis reveals shared gene signatures and molecular mechanisms between periodontitis and rheumatoid arthritis in the context of aging.Acta Odontol Scand202642627218PubTator, text miningPubMed
Causal Effects of Circulating Inflammatory Proteins on Postmenopausal Atrophic Vaginitis in European Populations: A Mendelian Randomization Study with Transcriptomic Validation.Int J Womens Health202642549019PubTator, text miningPubMed
[Bidirectional two-sample MR analysis of causal relationships between human inflammatory proteins and HS and keloids].Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi202642547441PubTator, text miningPubMed
Gamma Delta T Cells in Shrimp Allergy Express a Unique Cytotoxic Cytokine Profile.Clin Transl Allergy202642533289PubTator, text miningPubMed
Regulatory T cells establish an IL-10-IL10Rα immunometabolic checkpoint that limits HSL activation and lipolysis.bioRxiv202642523439PubTator, text miningPubMed

1 to 10 of 3,503

See all 3,503 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3587

GET https://conductscience.org/api/genes/v1/3587/patents?page=2