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IL12A: interleukin 12A

1 protein, 303 patents, 3 drugs, 167 trials, 3,129 NIH grants and 5,090 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL12AHGNC
Nameinterleukin 12AHGNC
NCBI Gene ID3592NCBI Gene
HGNC IDHGNC:5969HGNC
EnsemblENSG00000168811NCBI Gene
AliasesCLMF, IL-12A, NFSK, NKSF1, P35, p35NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P29459Interleukin-12 subunit alpha2194Ensembl, GeneID, HGNCUniProt

Patents 303

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4795154 A12026-08-26123P29459Espacenet
WO 2026171886 A12026-08-2010P29459Espacenet
EP 4774003 A12026-07-151P29459Espacenet
EP 4774398 A12026-07-1562P29459Espacenet
EP 4757832 A12026-06-17212P29459Espacenet
EP 4754237 A12026-06-109P29459Espacenet
JP 2026086743 A2026-05-26143P29459Espacenet
JP 2026082822 A2026-05-191P29459Espacenet
JP 2026074006 A2026-05-0123P29459Espacenet
JP 2026062601 A52026-04-2411P29459Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BRIAKINUMABCHEMBL1742995Interleukin-12 inhibitorINHIBITORChEMBL
EBDAROKIMABCHEMBL4650437Interleukin-12 inhibitorINHIBITORChEMBL
USTEKINUMABCHEMBL1201835Interleukin-12 inhibitorINHIBITORChEMBL

Trials 167

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07582991USTEKINUMABPHASE2ClinicalTrials.gov
NCT07529236USTEKINUMABClinicalTrials.gov
NCT07495644USTEKINUMABClinicalTrials.gov
NCT07444060USTEKINUMABClinicalTrials.gov
NCT07303686USTEKINUMABPHASE4ClinicalTrials.gov
NCT07263464USTEKINUMABClinicalTrials.gov
NCT07177118USTEKINUMABPHASE3ClinicalTrials.gov
NCT07149467USTEKINUMABPHASE3ClinicalTrials.gov
NCT07057856USTEKINUMABClinicalTrials.gov
NCT06997055USTEKINUMABClinicalTrials.gov

NIH grants 3129

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA010815Consolidated Basic Cancer Research Program192,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)112,025NIH's project files
P30CA016086Cancer Center Support Grant92,025NIH's project files
P30CA047904Cancer Center Support Grant82,025NIH's project files
R37CA230786Function of IL35+ B cells in pancreatic cancer62,025NIH's project files
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures62,025NIH's project files
P30CA016058Cancer Center Support Grant52,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility52,025NIH's project files

Papers 5090

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42813654PubTator, text miningPubMed
42698181PubTator, text miningPubMed
42666100PubTator, text miningPubMed
42648397PubTator, text miningPubMed
42619805PubTator, text miningPubMed
42491538PubTator, text miningPubMed
42479151PubTator, text miningPubMed
42379767PubTator, text miningPubMed
42349522PubTator, text miningPubMed
42326610PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license