Gene · 3597
IL13RA1: interleukin 13 receptor subunit alpha 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IL13RA1: interleukin 13 receptor subunit alpha 1. Genes, record 3597. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3597
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78552 | Interleukin-13 receptor subunit alpha-1 | 427 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents148
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12636345 B2 | 2026-05-26 | 3 | P78552 | Espacenet |
| EP 4705273 A2 | 2026-03-11 | 298 | P78552 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50170 | P78552 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8992 | P78552 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6880 | P78552 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16675 | P78552 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16738 | P78552 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2072 | P78552 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6699 | P78552 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2072 | P78552 | Espacenet |
1 to 10 of 148
See all 148 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| CINTREDEKIN BESUDOTOX | CHEMBL2108583 | Interleukin 13 receptor binding agent | BINDING AGENT |
Source ChEMBL
Trials9
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT00880061 | CINTREDEKIN BESUDOTOX | PHASE1 | ClinicalTrials.gov | |
| NCT00378235 | CINTREDEKIN BESUDOTOX | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT00089427 | CINTREDEKIN BESUDOTOX | PHASE1 | ClinicalTrials.gov | |
| NCT00076986 | CINTREDEKIN BESUDOTOX | PHASE3 | ClinicalTrials.gov | |
| NCT00053040 | CINTREDEKIN BESUDOTOX | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT00041587 | CINTREDEKIN BESUDOTOX | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT00036972 | CINTREDEKIN BESUDOTOX | PHASE1 | ClinicalTrials.gov | |
| NCT00024570 | CINTREDEKIN BESUDOTOX | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT00024557 | CINTREDEKIN BESUDOTOX | PHASE1 | ClinicalTrials.gov |
NIH grants1,255
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IL13RA1 papers | Newest fiscal year |
|---|---|---|---|
| R01AI051321 | Structure-based engineering of immune cytokine signaling | 9 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 7 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 6 | 2025 |
| U19AI070235 | Epithelial Genes in Allergic Inflammation | 6 | 2025 |
| P30CA012197 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R01AI065617 | Genetic and Epigenetic Programming of Allergic Airway Inflammation | 4 | 2025 |
| T32HL007698 | Interdisciplinary Training Program in Cardiovascular Disease | 4 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,255Source NIH's project files
See all 1,255 nih grantsPapers1,963
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Interleukin-1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis. | Adv Sci (Weinh) | 2026 | 42693602 | PubTator, text mining | PubMed |
| Interleukin13 Ameliorates Hepatocellular Steatosis via IL13Rα1/JNK/FOSL2 Signaling Pathway. | Cell Mol Gastroenterol Hepatol | 2026 | 42692359 | PubTator, text mining | PubMed |
| Cross-species transcriptomic evidence for peripheral-central immune crosstalk in atopic dermatitis. | Front Immunol | 2026 | 42433347 | PubTator, text mining | PubMed |
| Structure-guided modulation of the IL-4/IL-4Rα interface: molecular recognition, therapeutic antibodies, and small-molecule opportunities. | Bioorg Chem | 2026 | 42391811 | PubTator, text mining | PubMed |
| Identification and Prognostic Analysis of Immune-Related Genes Co-Regulated by Key Histone Modifications in Breast Cancer. | Curr Issues Mol Biol | 2026 | 42353587 | PubTator, text mining | PubMed |
| Dupilumab attenuate IL-4 and IL-13 synergistic effect on airway remodeling in asthma via blocking IL-4Rα/STAT6 axis. | Sci Rep | 2026 | 42218198 | PubTator, text mining | PubMed |
| ANKFN1 in skin fibroblasts may modulate mast cell activity and is associated with dupilumab response in atopic dermatitis. | Immunol Res | 2026 | 42062651 | PubTator, text mining | PubMed |
| Design of binder proteins specific to IL-13. | Int J Biol Macromol | 2026 | 41935810 | PubTator, text mining | PubMed |
| Interleukin 13 (IL-13) Signalling as a Potential Target for Cell Therapies in Liver Fibrosis. | Int J Mol Sci | 2026 | 41898594 | PubTator, text mining | PubMed |
| Unveiling the role of interleukin-13 in liver fibrosis of chronic hepatitis B patients: Development of a predictive model. | PLoS One | 2026 | 41871080 | PubTator, text mining | PubMed |
1 to 10 of 1,963
See all 1,963 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3597
GET https://conductscience.org/api/genes/v1/3597/patents?page=2