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IL16: interleukin 16

1 protein, 67 patents, 0 drugs, 0 trials, 2,826 NIH grants and 4,859 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL16HGNC
Nameinterleukin 16HGNC
NCBI Gene ID3603NCBI Gene
HGNC IDHGNC:5980HGNC
EnsemblENSG00000172349NCBI Gene
AliasesFLJ16806, FLJ42735, HsT19289, IL-16, LCF, NIL16, PRIL16, prIL-16NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q14005Pro-interleukin-161,3323Ensembl, GeneID, HGNCUniProt

Patents 67

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11282Q14005Espacenet
JP 2026000906 A2026-01-06295Q14005Espacenet
EP 4650780 A22025-11-194176Q14005Espacenet
US 12473363 B22025-11-18907Q14005Espacenet
EP 4640849 A22025-10-29542Q14005Espacenet
EP 4641201 A22025-10-293737Q14005Espacenet
JP 2025147176 A2025-10-0616742Q14005Espacenet
EP 4606428 A22025-08-2728Q14005Espacenet
JP 2025519096 A2025-06-24542Q14005Espacenet
JP 2025517969 A2025-06-123737Q14005Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2826

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition142,025NIH's project files
P30CA016672Cancer Center Support Grant122,025NIH's project files
P51OD011104Tulane National Primate Research Center82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
P30CA016058Cancer Center Support Grant72,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success72,025NIH's project files
P30CA016086Cancer Center Support Grant62,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant62,025NIH's project files
P30MH062512HIV Neurobehavioral Research Center62,025NIH's project files

Papers 4859

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823263PubTator, text miningPubMed
42804470PubTator, text miningPubMed
42784122PubTator, text miningPubMed
42720599PubTator, text miningPubMed
42701418PubTator, text miningPubMed
42690675PubTator, text miningPubMed
42684559PubTator, text miningPubMed
42676694PubTator, text miningPubMed
42675628PubTator, text miningPubMed
42664610PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license