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IL17A: interleukin 17A

1 protein, 418 patents, 11 drugs, 309 trials, 20,107 NIH grants and 80,010 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIL17AHGNC
Nameinterleukin 17AHGNC
NCBI Gene ID3605NCBI Gene
HGNC IDHGNC:5981HGNC
EnsemblENSG00000112115NCBI Gene
AliasesCTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q16552Interleukin-17A15544Ensembl, GeneID, HGNCUniProt

Patents 418

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086743 A2026-05-26159Q16552Espacenet
EP 4731677 A22026-04-2983Q16552Espacenet
EP 4705273 A22026-03-11291Q16552Espacenet
JP 2026505362 A2026-02-1335Q16552Espacenet
US 12546785 B22026-02-1034Q16552Espacenet
EP 4661884 A22025-12-1735Q16552Espacenet
EP 4650780 A22025-11-1919674Q16552Espacenet
US 12473363 B22025-11-18908Q16552Espacenet
EP 4641203 A22025-10-29778Q16552Espacenet
JP 2025147176 A2025-10-066899Q16552Espacenet

Drugs 11

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AFASEVIKUMABCHEMBL2109469Interleukin 17A inhibitorINHIBITORChEMBL
BIMEKIZUMABCHEMBL4297700Interleukin 17A inhibitorINHIBITORChEMBL
CJM-112CHEMBL4297926Interleukin 17A binding agentBINDING AGENTChEMBL
IXEKIZUMABCHEMBL1743034Interleukin 17A inhibitorINHIBITORChEMBL
IZOKIBEPCHEMBL4297686Interleukin 17A inhibitorINHIBITORChEMBL
M-1095CHEMBL4298023Interleukin 17A inhibitorINHIBITORChEMBL
PERAKIZUMABCHEMBL2109470Interleukin 17A inhibitorINHIBITORChEMBL
REMTOLUMABCHEMBL4297863Interleukin 17A inhibitorINHIBITORChEMBL
SECUKINUMABCHEMBL1743068Interleukin 17A inhibitorINHIBITORChEMBL
TIBULIZUMABCHEMBL3990000Interleukin 17A inhibitorINHIBITORChEMBL

Trials 309

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07477795SECUKINUMABPHASE2ClinicalTrials.gov
NCT07443956IXEKIZUMABClinicalTrials.gov
NCT07290036BIMEKIZUMABPHASE1ClinicalTrials.gov
NCT07243782SECUKINUMABClinicalTrials.gov
NCT07223138M-1095PHASE3ClinicalTrials.gov
NCT07219420BIMEKIZUMABPHASE3ClinicalTrials.gov
NCT07130331SECUKINUMABClinicalTrials.gov
NCT07109765SECUKINUMABClinicalTrials.gov
NCT07069270VUNAKIZUMABPHASE2ClinicalTrials.gov
NCT07007637M-1095PHASE3ClinicalTrials.gov

NIH grants 20107

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1072,025NIH's project files
P30CA016672Cancer Center Support Grant1002,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award982,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success752,025NIH's project files
P51OD011104Tulane National Primate Research Center632,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital612,025NIH's project files
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases562,025NIH's project files
ZIAAI001065India International Center for Excellence in Research542,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases522,025NIH's project files
R01HL117913The NOTCH Signaling Pathway in Large Vessel Vasculitis522,025NIH's project files

Papers 80010

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825901PubTator, text miningPubMed
42825488PubTator, text miningPubMed
42824810PubTator, text miningPubMed
42824352PubTator, text miningPubMed
42822776PubTator, text miningPubMed
42820044PubTator, text miningPubMed
42819676PubTator, text miningPubMed
42819443PubTator, text miningPubMed
42817968PubTator, text miningPubMed
42817588PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license