Gene · 362
AQP5: aquaporin 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. AQP5: aquaporin 5. Genes, record 362. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/362
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P55064 | Aquaporin-5 | 265 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents44
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025169942 A | 2025-11-14 | 821 | P55064 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 431 | P55064 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 431 | P55064 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 5959 | P55064 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 5959 | P55064 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 2425 | P55064 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 108930 | P55064 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 680 | P55064 | Espacenet |
| US 10772975 B2 | 2020-09-15 | 821 | P55064 | Espacenet |
| EP 3611183 A1 | 2020-02-19 | 8 | P55064 | Espacenet |
1 to 10 of 44
See all 44 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,123
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | AQP5 papers | Newest fiscal year |
|---|---|---|---|
| R01EY013462 | The Role of Aquaporins in Lens Structure and Function | 17 | 2025 |
| ZIADE000704 | Clinical and Mechanistic Investigations of Salivary Gland Dysfunction | 12 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 8 | 2025 |
| ZIADE000438 | Molecular Mechanisms Regulating Calcium Flux In Salivary Glands | 8 | 2025 |
| ZIADE000695 | Adeno-associated Virus Biology And Utilization For Gene Transfer | 8 | 2025 |
| R01DE022971 | THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATION | 7 | 2025 |
| R01DK101332 | Induction and Evolution of Metaplasia in the Stomach | 7 | 2025 |
| I01BX000930 | Oxyntic Atrophy and Novel Gastric Lineages. | 6 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 6 | 2025 |
1 to 10 of 1,123Source NIH's project files
See all 1,123 nih grantsPapers2,670
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Immunohistochemical cerebral cortex expression of aquaporin 4, aquaporin 5, aquaporin 9 Vasopressin and GFAP in saltwater drowning and freshwater drowning. | Int J Legal Med | 2026 | 42771035 | PubTator, text mining | PubMed |
| Assessment of Salivary Flow Patterns in Sjögren's Disease. | Oral Dis | 2026 | 42764807 | PubTator, text mining | PubMed |
| The expression of stemness markers in organoids according to histological subtypes of gastric cancer. | Korean J Clin Oncol | 2026 | 42687517 | PubTator, text mining | PubMed |
| Dynamic Changes in Serum Aquaporin-1 and Aquaporin-5 in Transient Tachypnea of the Newborn. | Int J Mol Sci | 2026 | 42653248 | PubTator, text mining | PubMed |
| Incomplete Intestinal Metaplasia as a High-Risk Clinical Phenotype in Gastric Carcinogenesis: Implications for Surveillance and Management. | Digestion | 2026 | 42611800 | PubTator, text mining | PubMed |
| Aquaporin 5 and Nuclear Factor Erythroid 2-Related Factor 2 Upregulation in Tumor and Stroma Is Associated with Poor Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer. | Med Princ Pract | 2026 | 42574300 | PubTator, text mining | PubMed |
| Senescent Alveolospheres: A Preliminary 3D Model for Exploring Epithelial Senescence and Pro-Fibrotic Signaling. | Int J Mol Sci | 2026 | 42511519 | PubTator, text mining | PubMed |
| Lute-Gen® Alleviates Dry Eye Disease and Modulates Nrf2/HO-1, TLR4/NF-κB/MAPK Signaling, and Aquaporin-Mediated Tear Homeostasis. | Antioxidants (Basel) | 2026 | 42510603 | PubTator, text mining | PubMed |
Retraction notice to "Development of novel prognostic protein signatures in ovarian cancer: Molecular structure and immune function of AQP5 protein and CTDP1 protein" [Int. J. Biol. Macromol. 310 (2025) 143474]. | Int J Biol Macromol | 2026 | 42486759 | PubTator, text mining | PubMed |
| Evaluation of pilocarpine effects on sweat proteome. | J Proteomics | 2026 | 42437570 | PubTator, text mining | PubMed |
1 to 10 of 2,670
See all 2,670 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/362
GET https://conductscience.org/api/genes/v1/362/patents?page=2