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CXCL10: C-X-C motif chemokine ligand 10

1 protein, 251 patents, 2 drugs, 7 trials, 16,213 NIH grants and 42,049 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCXCL10HGNC
NameC-X-C motif chemokine ligand 10HGNC
NCBI Gene ID3627NCBI Gene
HGNC IDHGNC:10637HGNC
EnsemblENSG00000169245NCBI Gene
AliasesC7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P02778C-X-C motif chemokine 10986Ensembl, GeneID, HGNCUniProt

Patents 251

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026120675 A2026-07-22754P02778Espacenet
EP 4705273 A22026-03-11242P02778Espacenet
EP 4705329 A12026-03-116P02778Espacenet
JP 2026503880 A2026-02-028P02778Espacenet
JP 2025172140 A2025-11-208P02778Espacenet
EP 4650780 A22025-11-194357P02778Espacenet
JP 2025166001 A2025-11-053P02778Espacenet
EP 4641203 A22025-10-29142P02778Espacenet
JP 2025147176 A2025-10-063796P02778Espacenet
JP 2025147176 A2025-10-0616695P02778Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ELDELUMABCHEMBL2109664C-X-C motif chemokine 10 inhibitorINHIBITORChEMBL
NI-0801CHEMBL2109379C-X-C motif chemokine 10 inhibitorINHIBITORChEMBL

Trials 7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01466374ELDELUMABPHASE2ClinicalTrials.gov
NCT01430429NI-0801PHASE2ClinicalTrials.gov
NCT01294410ELDELUMABPHASE2ClinicalTrials.gov
NCT01244607NI-0801PHASE1ClinicalTrials.gov
NCT01017367ELDELUMABPHASE2ClinicalTrials.gov
NCT00656890ELDELUMABPHASE2ClinicalTrials.gov
NCT00295282ELDELUMABPHASE1ClinicalTrials.gov

NIH grants 16213

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1142,025NIH's project files
P30CA008748Cancer Center Support Grant1112,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award962,025NIH's project files
P30CA047904Cancer Center Support Grant552,025NIH's project files
P51OD011104Tulane National Primate Research Center542,025NIH's project files
P51OD011132Emory National Primate Research Center522,025NIH's project files
P30MH062512HIV Neurobehavioral Research Center492,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition472,025NIH's project files
P30AI027763UCSF-Bay Area Center for AIDS Research432,025NIH's project files
P30CA016058Cancer Center Support Grant352,025NIH's project files

Papers 42049

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825992PubTator, text miningPubMed
42823263PubTator, text miningPubMed
42821609PubTator, text miningPubMed
42820287PubTator, text miningPubMed
42818784PubTator, text miningPubMed
42816734PubTator, text miningPubMed
42814769PubTator, text miningPubMed
42814219PubTator, text miningPubMed
42812837PubTator, text miningPubMed
42808783PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license