Gene · 3636
INPPL1: inositol polyphosphate phosphatase like 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. INPPL1: inositol polyphosphate phosphatase like 1. Genes, record 3636. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3636
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15357 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | 1,258 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026013165 A1 | 2026-01-15 | 1 | O15357 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49819 | O15357 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3867 | O15357 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3436 | O15357 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3436 | O15357 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3867 | O15357 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 40381 | O15357 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 143352 | O15357 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 5520 | O15357 | Espacenet |
| US 10928397 B2 | 2021-02-23 | 17 | O15357 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,039
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | INPPL1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 6 | 2025 |
| P30DA018343 | Yale/NIDA Neuroproteomics Center | 5 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016359 | Cancer Center Support Grant | 3 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,039Source NIH's project files
See all 1,039 nih grantsPapers1,456
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| When X Does Not Mark the Spot: Autosomal Dominant and Recessive Forms of Renal Hypophosphatemic Rickets and Osteomalacia. | Curr Osteoporos Rep | 2026 | 42412262 | PubTator, text mining | PubMed |
| LPIN3 emerges as a diagnostic biomarker in Moyamoya disease revealing immune-lipid metabolic crosstalk. | Front Genet | 2026 | 42338983 | PubTator, text mining | PubMed |
| Aimed at Subtype Discrimination but Yielding a Shared Marker: Integrative Analysis of Blood Transcriptomes Reveals Upregulated TLR5 as a Potential Biomarker for IBD. | Clin Exp Gastroenterol | 2026 | 42112146 | PubTator, text mining | PubMed |
| Phosphatidylinositol 3,4-bisphosphate emerges as a lipid mediator linking oxidative stress to DNA damage. | J Biochem | 2026 | 41955560 | PubTator, text mining | PubMed |
| Advances in the biological functions of miR‑205 in various diseases (Review). | Mol Med Rep | 2026 | 41860043 | PubTator, text mining | PubMed |
Active Macropinocytosis, Lipid Catabolism, and Exhausting Immune Microenvironment of Ascites Tumor Cells Are Involved in Resistance to Platinum-Based Therapy in Patients With High-Grade Serous Ovarian Cancer. | MedComm (2020) | 2026 | 41799929 | PubTator, text mining | PubMed |
| Targeted biologics for TNBC: Advances in nanobodies, antibodies, peptides, and aptamers. | Mol Ther Oncol | 2026 | 41716468 | PubTator, text mining | PubMed |
| Interplay between obesity-associated insulin resistance and immune system through the lens of evolutionary medicine. | Mol Metab | 2026 | 41692338 | PubTator, text mining | PubMed |
| Structural insights into SHIP2 reveal its membrane regulatory mechanisms. | Protein Sci | 2026 | 41676923 | PubTator, text mining | PubMed |
| Quantitative MRI Evaluation of Hemispheric Asymmetry in Circle of Willis Artery Diameters. | J Neuroimaging | 2026 | 41635955 | PubTator, text mining | PubMed |
1 to 10 of 1,456
See all 1,456 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3636
GET https://conductscience.org/api/genes/v1/3636/patents