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Gene · 3636

INPPL1: inositol polyphosphate phosphatase like 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. INPPL1: inositol polyphosphate phosphatase like 1. Genes, record 3636. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3636

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Gene

Symbol
INPPL1
HGNC
Name
inositol polyphosphate phosphatase like 1
HGNC
NCBI Gene ID
3636
NCBI Gene
HGNC ID
HGNC:6080
HGNC
Ensembl
ENSG00000165458
NCBI Gene
Aliases
OPSMD, SHIP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15357Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 21,25811Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026013165 A12026-01-151O15357Espacenet
JP 2026004568 A2026-01-1449819O15357Espacenet
EP 4650780 A22025-11-193867O15357Espacenet
EP 4641201 A22025-10-293436O15357Espacenet
JP 2025517969 A2025-06-123436O15357Espacenet
JP 2025517970 A2025-06-123867O15357Espacenet
US 11446398 B22022-09-2040381O15357Espacenet
JP 2022524081 A2022-04-27143352O15357Espacenet
US 11078247 B22021-08-035520O15357Espacenet
US 10928397 B22021-02-2317O15357Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,039

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleINPPL1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA008748Cancer Center Support Grant72025
P30CA016058Cancer Center Support Grant62025
P30DA018343Yale/NIDA Neuroproteomics Center52025
P30CA014051Cancer Center Support (Core) Grant42025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
P30DK063491Diabetes Research Center (DRC)42025
P30CA015704Cancer Center Support Grant32025
P30CA016359Cancer Center Support Grant32025
P30CA046934University of Colorado Cancer Center Support Grant32025

1 to 10 of 1,039Source NIH's project files

See all 1,039 nih grants

Papers1,456

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
When X Does Not Mark the Spot: Autosomal Dominant and Recessive Forms of Renal Hypophosphatemic Rickets and Osteomalacia.Curr Osteoporos Rep202642412262PubTator, text miningPubMed
LPIN3 emerges as a diagnostic biomarker in Moyamoya disease revealing immune-lipid metabolic crosstalk.Front Genet202642338983PubTator, text miningPubMed
Aimed at Subtype Discrimination but Yielding a Shared Marker: Integrative Analysis of Blood Transcriptomes Reveals Upregulated TLR5 as a Potential Biomarker for IBD.Clin Exp Gastroenterol202642112146PubTator, text miningPubMed
Phosphatidylinositol 3,4-bisphosphate emerges as a lipid mediator linking oxidative stress to DNA damage.J Biochem202641955560PubTator, text miningPubMed
Advances in the biological functions of miR‑205 in various diseases (Review).Mol Med Rep202641860043PubTator, text miningPubMed
Active Macropinocytosis, Lipid Catabolism, and Exhausting Immune Microenvironment of Ascites Tumor Cells Are Involved in Resistance to Platinum-Based Therapy in Patients With High-Grade Serous Ovarian Cancer.
MedComm (2020)202641799929PubTator, text miningPubMed
Targeted biologics for TNBC: Advances in nanobodies, antibodies, peptides, and aptamers.Mol Ther Oncol202641716468PubTator, text miningPubMed
Interplay between obesity-associated insulin resistance and immune system through the lens of evolutionary medicine.Mol Metab202641692338PubTator, text miningPubMed
Structural insights into SHIP2 reveal its membrane regulatory mechanisms.Protein Sci202641676923PubTator, text miningPubMed
Quantitative MRI Evaluation of Hemispheric Asymmetry in Circle of Willis Artery Diameters.J Neuroimaging202641635955PubTator, text miningPubMed

1 to 10 of 1,456

See all 1,456 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3636

GET https://conductscience.org/api/genes/v1/3636/patents