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PDX1: pancreatic and duodenal homeobox 1

1 protein, 91 patents, 0 drugs, 0 trials, 3,957 NIH grants and 6,194 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPDX1HGNC
Namepancreatic and duodenal homeobox 1HGNC
NCBI Gene ID3651NCBI Gene
HGNC IDHGNC:6107HGNC
EnsemblENSG00000139515NCBI Gene
AliasesGSF, IDX-1, IPF1, IUF-1, IUF1, MODY4, PAGEN1, PDX-1, STF-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P52945Pancreas/duodenum homeobox protein 12832Ensembl, GeneID, HGNCUniProt

Patents 91

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4771163 A12026-07-084P52945Espacenet
JP 2026004568 A2026-01-1457040P52945Espacenet
EP 4669359 A12025-12-314P52945Espacenet
EP 4641201 A22025-10-2910722P52945Espacenet
JP 2025147176 A2025-10-0615479P52945Espacenet
JP 2025517969 A2025-06-1210722P52945Espacenet
WO 2025072849 A12025-04-03294P52945Espacenet
EP 4525933 A22025-03-266P52945Espacenet
JP 2025028160 A2025-02-2815479P52945Espacenet
EP 4502164 A12025-02-0566P52945Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3957

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK020593Vanderbilt Diabetes Research Center432,025NIH's project files
P30CA008748Cancer Center Support Grant422,025NIH's project files
P30DK036836Diabetes Research Center362,025NIH's project files
P30CA016672Cancer Center Support Grant342,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)322,025NIH's project files
P30DK019525University of Pennsylvania Diabetes Research Center312,025NIH's project files
P30DK020595Diabetes Research and Training Center282,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)272,025NIH's project files
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases272,025NIH's project files
U01CA210240Pancreatic Cancer Detection Consortium242,025NIH's project files

Papers 6194

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42772346PubTator, text miningPubMed
42770314PubTator, text miningPubMed
42766004PubTator, text miningPubMed
42758828PubTator, text miningPubMed
42752562PubTator, text miningPubMed
42730891PubTator, text miningPubMed
42728345PubTator, text miningPubMed
42721957PubTator, text miningPubMed
42677697PubTator, text miningPubMed
42660425PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license