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IREB2: iron responsive element binding protein 2
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Gene · 3658

Papers2,039

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,039

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TitleJournalYearPMIDFound bySource
Statement of Retraction: MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2.Bioengineered202642821367PubTator, text miningPubMed
Targeting Iron Regulatory Protein 2 in Tumor-associated Macrophages Activates Antitumor Immunity in NSCLC via Modulating SphK1-PD-L1 Axis.Int J Biol Sci202642807526PubTator, text miningPubMed
Realgar Transforming Solution Triggers Ferroptosis-Associated Death in NB4 Leukemia Cells through Disruption of Iron Homeostasis and Suppression of the SLC7A11/GPX4 Axis.Biol Pharm Bull202642716792PubTator, text miningPubMed
Chemogenomic maps reveal a PRDX1-dependent iron-damage axis in the DNA damage response.Nat Chem Biol202642711491PubTator, text miningPubMed
ADHD-anchored partitioning of non-small cell lung cancer genetic covariance identifies CLPTM1L and suggestive innate-immune signals.Front Immunol202642661613PubTator, text miningPubMed
Integrated multi-omics profiling of amniotic fluid identifies predictive biomarkers for fetal growth restriction trajectories.Ann Med202642603261PubTator, text miningPubMed
Polyamines buffer labile iron to suppress ferroptosis.Cell202642600612PubTator, text miningPubMed
EGR1 promotes ferroptosis in endometrial cancer cells by increasing NOX4 transcription.Histol Histopathol202642478614PubTator, text miningPubMed
Germline determinants of risk and molecular subtype in young-onset lung cancer.medRxiv202642465903PubTator, text miningPubMed
Iron biomarkers for prognosis, diagnosis, and therapeutic insight in colorectal cancer.Biomed Pharmacother202642442308PubTator, text miningPubMed
Correction: Single-cell atlas reveals the key role of pro-inflammatory IREB2⁺ microglia subsets in the microenvironment of Alzheimer's disease.Clin Exp Med202642366234PubTator, text miningPubMed
Hypoxia-induced lnc-IRP drives oxaliplatin resistance in colorectal cancer through IRP2 sequestration and iron metabolism reprogramming.J Transl Med202642332736PubTator, text miningPubMed
A novel HPV E6/E7-regulated long noncoding RNA CRL suppresses cervical intraepithelial neoplasia progression by attenuating ferroptosis.Hum Cell202642323795PubTator, text miningPubMed
HERC2 as a bidirectional iron metabolism switch: Synergistic NCOA4 stabilization and FBXL5 degradation drive ferroptosis-cascaded hepatotoxicity in Nd2O3 nanoparticles exposure.Free Radic Biol Med202642320848PubTator, text miningPubMed
Genetic susceptibility to COPD: Systematic review, bibliometric analysis and meta-analysis of SERPINA1, HHIP, IREB2, SFTPD, and FAM13A.Respir Investig202642269416PubTator, text miningPubMed
Single-cell atlas reveals the key role of pro-inflammatory IREB2⁺ microglia subsets in the microenvironment of Alzheimer's disease.Clin Exp Med202642159858PubTator, text miningPubMed
Ectopic Tyrosinase Perturbs Cellular Iron Homeostasis.ACS Chem Biol202642145234PubTator, text miningPubMed
SARS-CoV-2 Delta, not Omicron, drives Transferrin receptor-1 upregulation, inflammatory activation, and viral persistence in macrophages.Biomed Pharmacother202642134243PubTator, text miningPubMed
Iron: Regulation, redox homeostasis, and ferroptosis in cancer.Ferroptosis Oxid Stress202642099806PubTator, text miningPubMed
Bioinformatics analysis and qRT-PCR validation of iron metabolism-related genes in pediatric asthma.PLoS One202641984875PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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