Gene · 3660
IRF2: interferon regulatory factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IRF2: interferon regulatory factor 2. Genes, record 3660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3660
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P14316 | Interferon regulatory factor 2 | 349 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 50057 | P14316 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11044 | P14316 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11473 | P14316 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15170 | P14316 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11473 | P14316 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11044 | P14316 | Espacenet |
| JP 2025506185 A | 2025-03-07 | 36 | P14316 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15170 | P14316 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15170 | P14316 | Espacenet |
| EP 4479067 A2 | 2024-12-25 | 36 | P14316 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,791
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IRF2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 20 | 2025 |
| P30AG017265 | USC/UCLA Center on Biodemography and Population Health | 9 | 2025 |
| ZIAHD001310 | Gene Regulation In The Immune System | 7 | 2025 |
| P01CA019014 | Viral Oncogenesis, Latency, and Replication | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| R01AI124346 | Innate immune signaling and stress response | 6 | 2025 |
| R37AI101935 | Inflammatory Caspases in Innate Immunity and Inflammation | 6 | 2025 |
| U19AI089992 | Immune signatures of vaccine responses in vulnerable populations | 6 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| T32CA009621 | Surgical Oncology Basic Science and Translational Research Training Program | 5 | 2025 |
1 to 10 of 1,791Source NIH's project files
See all 1,791 nih grantsPapers2,395
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: The Study of Muscle, Mobility and Aging. | Arthritis Rheumatol | 2026 | 42750572 | PubTator, text mining | PubMed |
| A neuron-distributed DEK integrates ac4C modification and neuroinflammation in pathogenesis of Parkinson disease: evidence from Mendelian randomization, multi-omics and in vitro validation. | Front Neurosci | 2026 | 42745872 | PubTator, text mining | PubMed |
| Deciphering HPV-Associated Immune Evasion in Cervical Cancer Through Multi-Omics Profiling and Computational Screening. | Anal Cell Pathol (Amst) | 2026 | 42635083 | PubTator, text mining | PubMed |
| Regulatory role of IRF2 in proliferation and invasion of nasopharyngeal carcinoma and its underlying mechanism. | iScience | 2026 | 42541166 | PubTator, text mining | PubMed |
| Orthogonal CRISPR screens and human liver chimeric mice identify hepatitis B virus host factors. | bioRxiv | 2026 | 42539305 | PubTator, text mining | PubMed |
| Patient-derived organoid-immune co-cultures integrated with multi-omics reveal immunotherapy resistance mechanisms in urothelial carcinoma. | Imeta | 2026 | 42491341 | PubTator, text mining | PubMed |
| Integrative single-cell and spatial transcriptomics combined with machine learning to discover complement-associated biomarkers in temporal lobe epilepsy with hippocampal sclerosis. | Funct Integr Genomics | 2026 | 42458112 | PubTator, text mining | PubMed |
| In search of dependencies in myeloma, consider IRF2 too. | Blood | 2026 | 42348229 | PubTator, text mining | PubMed |
| The role of interferon regulatory factors in atherosclerosis: from cell type-specific mechanisms to therapeutic strategies. | Front Cell Dev Biol | 2026 | 42343899 | PubTator, text mining | PubMed |
| The paradox of action: Trajectories in distress, meaning, and gene regulation following self-directed activist engagement among Black women. | SSM Ment Health | 2026 | 42312185 | PubTator, text mining | PubMed |
1 to 10 of 2,395
See all 2,395 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3660
GET https://conductscience.org/api/genes/v1/3660/patents?page=2