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IRF4: interferon regulatory factor 4

1 protein, 44 patents, 0 drugs, 0 trials, 5,077 NIH grants and 8,428 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIRF4HGNC
Nameinterferon regulatory factor 4HGNC
NCBI Gene ID3662NCBI Gene
HGNC IDHGNC:6119HGNC
EnsemblENSG00000137265NCBI Gene
AliasesIMD131, LSIRF, MUM1, NF-EM5, SHEP8NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15306Interferon regulatory factor 445120Ensembl, GeneID, HGNCUniProt

Patents 44

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4661970 A12025-12-1762153Q15306Espacenet
EP 4641201 A22025-10-2910711Q15306Espacenet
EP 4641202 A22025-10-295770Q15306Espacenet
JP 2025147176 A2025-10-0615172Q15306Espacenet
JP 2025517969 A2025-06-1210711Q15306Espacenet
JP 2025028160 A2025-02-2815172Q15306Espacenet
KR 1020250017231 A2025-02-045770Q15306Espacenet
KR 1020250010750 A2025-01-2115172Q15306Espacenet
KR 1020240151659 A2024-10-183Q15306Espacenet
US 12115190 B22024-10-151Q15306Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5077

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant662,025NIH's project files
P30CA016672Cancer Center Support Grant472,025NIH's project files
ZIASC000550Lymphoma Disease Discovery and Definition322,025NIH's project files
ZIABC011070Hematopathology Diagnosis262,025NIH's project files
P01CA155258Integrative Oncogenomics of Multiple Myeloma232,025NIH's project files
R01AI057459Allergic inflammation and Transcriptional Regulation in Th9 cells212,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award212,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant202,025NIH's project files
P30CA086862Cancer Center Support Grant192,025NIH's project files
P30CA091842Cancer Center Support Grant182,025NIH's project files

Papers 8428

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814553PubTator, text miningPubMed
42806415PubTator, text miningPubMed
42804764PubTator, text miningPubMed
42803950PubTator, text miningPubMed
42802436PubTator, text miningPubMed
42791263PubTator, text miningPubMed
42786293PubTator, text miningPubMed
42775020PubTator, text miningPubMed
42768223PubTator, text miningPubMed
42756106PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license