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Gene · 3663

IRF5: interferon regulatory factor 5

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. IRF5: interferon regulatory factor 5. Genes, record 3663. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/3663

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
IRF5
HGNC
Name
interferon regulatory factor 5
HGNC
NCBI Gene ID
3663
NCBI Gene
HGNC ID
HGNC:6120
HGNC
Ensembl
ENSG00000128604
NCBI Gene
Aliases
IRF-5, SLEB10
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13568Interferon regulatory factor 54981Ensembl, GeneID, HGNC

Source UniProt

Patents72

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0368Q13568Espacenet
JP 2025147176 A2025-10-0615173Q13568Espacenet
KR 1020250067969 A2025-05-1525Q13568Espacenet
JP 2025028160 A2025-02-2815173Q13568Espacenet
KR 1020250010750 A2025-01-2115173Q13568Espacenet
US 12133879 B22024-11-0568Q13568Espacenet
JP 2024153644 A2024-10-2925Q13568Espacenet
JP 2024123008 A2024-09-106647Q13568Espacenet
JP 2024123008 A2024-09-106649Q13568Espacenet
JP 2024123008 A2024-09-106655Q13568Espacenet

1 to 10 of 72

See all 72 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,893

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
R01AI024717Genetic Linkage in Lupus282025
U54GM104938Oklahoma Shared Clinical and Translational Resources152025
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)132025
U01DK062422Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations92025
R01AI046712Activation of Macrophages in Human Autoimmune Diseases82025
P30CA023108Cancer Center Support Grant72025
P30DK034989Yale Liver Center72025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital72025
R01AI044938Inhibition of STAT3 and inflammatory cytokine production72025
R01DK099097Functional outcomes of inflammatory bowel disease associated variants72025

1 to 10 of 2,893Source NIH's project files

See all 2,893 nih grants

Papers4,211

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42781718PubTator, text miningPubMed
42778089PubTator, text miningPubMed
42737545PubTator, text miningPubMed
42726758PubTator, text miningPubMed
42653386PubTator, text miningPubMed
42560765PubTator, text miningPubMed
42527560PubTator, text miningPubMed
42509821PubTator, text miningPubMed
42491523PubTator, text miningPubMed
42488650PubTator, text miningPubMed

1 to 10 of 4,211

See all 4,211 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3663

GET https://conductscience.org/api/genes/v1/3663/patents?page=2