ConductScience.org, home

Gene · 3669

ISG20: interferon stimulated exonuclease gene 20

11 sourcesgene-search-2026-11-11-0.1.0

Download JSON
Cite this record

ConductScience Library. ISG20: interferon stimulated exonuclease gene 20. Genes, record 3669. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/3669

On this page

Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
ISG20
HGNC
Name
interferon stimulated exonuclease gene 20
HGNC
NCBI Gene ID
3669
NCBI Gene
HGNC ID
HGNC:6130
HGNC
Ensembl
ENSG00000172183
NCBI Gene
Aliases
CD25, HEM45
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96AZ6Interferon-stimulated gene 20 kDa protein1812Ensembl, GeneID, HGNC

Source UniProt

Patents49

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450075Q96AZ6Espacenet
JP 2026004568 A2026-01-1450076Q96AZ6Espacenet
US 11892452 B22024-02-0652Q96AZ6Espacenet
US 11446398 B22022-09-2041140Q96AZ6Espacenet
US 11446398 B22022-09-2041142Q96AZ6Espacenet
JP 2022524081 A2022-04-27144111Q96AZ6Espacenet
JP 2022524081 A2022-04-27144113Q96AZ6Espacenet
US 11078247 B22021-08-035594Q96AZ6Espacenet
US 11016093 B22021-05-2552Q96AZ6Espacenet
WO 2020043864 A12020-03-051227Q96AZ6Espacenet

1 to 10 of 49

See all 49 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,395

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant192025
P30CA008748Cancer Center Support Grant182025
ZIABC010301Development of Recombinant Toxins to Treat Hematologic Malignancies132025
ZICSC009372Flow cytometric analysis of benign and malignant tumors102025
P51OD011132Emory National Primate Research Center92025
P30CA047904Cancer Center Support Grant82025
UL1TR001863Yale Clinical and Translational Science Award82025
ZICBC011104Flow cytometric evaluation of biomarkers72025
P30AI027763UCSF-Bay Area Center for AIDS Research62025
P30CA015704Cancer Center Support Grant62025

1 to 10 of 2,395Source NIH's project files

See all 2,395 nih grants

Papers4,236

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820287PubTator, text miningPubMed
42815679PubTator, text miningPubMed
42643694PubTator, text miningPubMed
42636619PubTator, text miningPubMed
42579335PubTator, text miningPubMed
42577265PubTator, text miningPubMed
42548058PubTator, text miningPubMed
42542175PubTator, text miningPubMed
42536250PubTator, text miningPubMed
42529171PubTator, text miningPubMed

1 to 10 of 4,236

See all 4,236 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3669

GET https://conductscience.org/api/genes/v1/3669/patents?page=2