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ITGA2: integrin subunit alpha 2

1 protein, 62 patents, 1 drug, 4 trials, 3,634 NIH grants and 5,966 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolITGA2HGNC
Nameintegrin subunit alpha 2HGNC
NCBI Gene ID3673NCBI Gene
HGNC IDHGNC:6137HGNC
EnsemblENSG00000164171NCBI Gene
AliasesBR, CD49B, FMAIT3, GPIa, HPA-5, VLA-2, VLAA2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P17301Integrin alpha-21,18123Ensembl, GeneID, HGNCUniProt

Patents 62

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449962P17301Espacenet
EP 4650780 A22025-11-193747P17301Espacenet
EP 4641202 A22025-10-29195P17301Espacenet
EP 4641203 A22025-10-29125P17301Espacenet
WO 2025153055 A12025-07-2412P17301Espacenet
JP 2025103749 A2025-07-091P17301Espacenet
JP 2025517967 A2025-06-12125P17301Espacenet
JP 2025517970 A2025-06-123747P17301Espacenet
JP 2025032204 A2025-03-1130060P17301Espacenet
KR 1020250017230 A2025-02-04125P17301Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
VATELIZUMABCHEMBL1743086Integrin alpha-2 antagonistANTAGONISTChEMBL

Trials 4

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02306811VATELIZUMABPHASE2ClinicalTrials.gov
NCT02222948VATELIZUMABPHASE2ClinicalTrials.gov
NCT01861249VATELIZUMABPHASE2ClinicalTrials.gov
NCT01659138VATELIZUMABPHASE2ClinicalTrials.gov

NIH grants 3634

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant252,025NIH's project files
P30CA008748Cancer Center Support Grant162,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases102,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center92,025NIH's project files
P30CA091842Cancer Center Support Grant92,025NIH's project files
P30CA068485Cancer Center Support Grant82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202862,025NIH's project files
P30CA093373Cancer Center Support Grant P3062,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant62,025NIH's project files

Papers 5966

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42783701PubTator, text miningPubMed
42749459PubTator, text miningPubMed
42747603PubTator, text miningPubMed
42723078PubTator, text miningPubMed
42710178PubTator, text miningPubMed
42698600PubTator, text miningPubMed
42689987PubTator, text miningPubMed
42682420PubTator, text miningPubMed
42652217PubTator, text miningPubMed
42618857PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license