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Gene · 3675

ITGA3: integrin subunit alpha 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ITGA3: integrin subunit alpha 3. Genes, record 3675. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3675

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Gene

Symbol
ITGA3
HGNC
Name
integrin subunit alpha 3
HGNC
NCBI Gene ID
3675
NCBI Gene
HGNC ID
HGNC:6139
HGNC
Ensembl
ENSG00000005884
NCBI Gene
Aliases
CD49C, CD49c, FRP-2, GAP-B3, GAPB3, ILNEB, JEB7, MSK18, VCA-2, VL3A, VLA3a
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P26006Integrin alpha-31,0510Ensembl, GeneID, HGNC

Source UniProt

Patents80

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026516931 A2026-05-2745P26006Espacenet
JP 2026004568 A2026-01-1449970P26006Espacenet
WO 2025259600 A22025-12-1811P26006Espacenet
EP 4641201 A22025-10-294581P26006Espacenet
EP 4611808 A12025-09-1045P26006Espacenet
JP 2025529142 A2025-09-042135P26006Espacenet
US 12371689 B22025-07-292135P26006Espacenet
JP 2025517969 A2025-06-124581P26006Espacenet
US 12291562 B22025-05-0671P26006Espacenet
US 12000003 B22024-06-0424P26006Espacenet

1 to 10 of 80

See all 80 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,647

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleITGA3 papersNewest fiscal year
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant72025
R01DK069921The Laminin Receptors in Kidney Disease52025
P30CA010815Consolidated Basic Cancer Research Program42025
P30CA016087Cancer Center Support Grant42025
P30CA022453CANCER CENTER SUPPORT GRANT42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
P30CA225520Stephenson Cancer Center - Cancer Center Support Grant42025
I01BX002025Molecular Mechanisms of Kidney Fibrosis32025

1 to 10 of 1,647Source NIH's project files

See all 1,647 nih grants

Papers2,788

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated reverse network toxicology and experimental validation identify PTP4A3 as a key target of Benzo[a]pyrene in prostate cancer.Chem Biol Interact202642805285PubTator, text miningPubMed
Functional alterations of peripheral blood-derived mesenchymal stem cells in erosive hand osteoarthritis: modulation by resveratrol.Clin Exp Rheumatol202642752324PubTator, text miningPubMed
Trio-Based Whole-Exome Sequencing Identifies Convergent Epithelial Junction-Related Pathways in Syndromic Hidradenitis Suppurativa.Dermatology202642709635PubTator, text miningPubMed
Integrin α3 (ITGA3) expression across breast cancer subtypes: Prognosis and therapeutic relevance.Cancer Pathog Ther202642699527PubTator, text miningPubMed
Biomimetic Hydrogels with Nucleus Pulposus-like Viscoelasticity and ECM Peptides for Discogenic Differentiation of Stem Cells.ACS Biomater Sci Eng202642695568PubTator, text miningPubMed
Myofibroblastic CAF and Malignant Ductal Cell Crosstalk Drives Epithelial-Mesenchymal Transition and Progression in Pancreatic Ductal Adenocarcinoma via THBS2-SDC/Integrin Axes.Int J Mol Sci202642589604PubTator, text miningPubMed
Expanding the phenotypic spectrum of ILNEB: Absence of classic dermatologic findings in a 12-year-old girl with homozygous ITGA3 p.Arg274Gln.JAAD Case Rep202642569287PubTator, text miningPubMed
Uncovering molecular and functional dynamics of human hematopoietic stem cells during in vitro culture for cell therapy manufacturing.Cytotherapy202642556173PubTator, text miningPubMed
A vesicular trafficking pathway mediated by N-ethylmaleimide-sensitive factor governs integrin maturation and podocyte integrity.Kidney Int202642492856PubTator, text miningPubMed
Oncogenic Gαq Signaling Remodels the Tumor Surfaceome and Rewires Intracellular Networks in Uveal Melanoma Models.Cancers (Basel)202642352426PubTator, text miningPubMed

1 to 10 of 2,788

See all 2,788 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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