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Gene · 368

ABCC6: ATP binding cassette subfamily C member 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCC6: ATP binding cassette subfamily C member 6. Genes, record 368. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/368

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Gene

Symbol
ABCC6
HGNC
Name
ATP binding cassette subfamily C member 6
HGNC
NCBI Gene ID
368
NCBI Gene
HGNC ID
HGNC:57
HGNC
Ensembl
ENSG00000091262
NCBI Gene
Aliases
ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95255ATP-binding cassette sub-family C member 61,5034Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19245O95255Espacenet
JP 2026067851 A2026-04-21408O95255Espacenet
JP 2026004568 A2026-01-1438436O95255Espacenet
EP 4641201 A22025-10-29202O95255Espacenet
JP 2025529142 A2025-09-04204O95255Espacenet
US 12371689 B22025-07-29204O95255Espacenet
JP 2025517969 A2025-06-12202O95255Espacenet
JP 2025062604 A2025-04-147747O95255Espacenet
WO 2024214081 A12024-10-17245O95255Espacenet
JP 2023521663 A2023-05-25407O95255Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants792

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCC6 papersNewest fiscal year
P20GM113134COBRE-DIABETES132025
P30ES006694Southwest Environmental Health Sciences Center72025
P30CA034196Cancer Center Support (CORE) Grant52025
UL1TR001863Yale Clinical and Translational Science Award52025
ZIAHG000215Human Biochemical Genetics52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025
P30CA016672Cancer Center Support Grant42025
P30CA056036Translational Research in Cancer42025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)32025
T32ES007091Training in Environmental Toxicology of Human Disease32025

1 to 10 of 792Source NIH's project files

See all 792 nih grants

Papers1,933

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Skeletal effects of 5-year high-dose cyclical etidronate in patients with pseudoxanthoma elasticum.Bone202742744197PubTator, text miningPubMed
Increased risk of cerebrovascular events in pseudoxanthoma elasticum.Int J Stroke202642803115PubTator, text miningPubMed
Retinal Features and Preserved Vision in ENPP1 Deficiency: Long-Term Insights from Multimodal Imaging and Electrophysiology.Int J Mol Sci202642794828PubTator, text miningPubMed
Perinatal Diagnosis of Generalized Arterial Calcification of Infancy: First Genetically Confirmed ENPP1 Case in an Egyptian Fetus.J Genet Eng Biotechnol202642749424PubTator, text miningPubMed
Hereditary connective tissue disorders in unselected patients with spontaneous cervical artery dissection: a targeted next generation sequencing approach and systematic review.Neurol Sci202642684449PubTator, text miningPubMed
A cross-platform validated biomarker signature for mucoepidermoid carcinoma identified by integrated WGCNA and machine learning.Comput Biol Chem202642664892PubTator, text miningPubMed
ABCC6 in Cellular Metabolic Homeostasis: Biochemical Links to Extracellular Nucleotide Signaling, Mitochondrial Stress, and Senescence.Cell Biochem Biophys202642631824PubTator, text miningPubMed
Whole-exome sequencing identifies matrisomal gene associations in monogenic cerebral small vessel disease.J Neurol202642481886PubTator, text miningPubMed
ABCC6-associated retinopathy presenting with a pattern dystrophy phenotype.Can J Ophthalmol202642457148PubTator, text miningPubMed
Inherited retinal disease genes with dual inheritance patterns: insights from the IRD-PT registry.J Med Genet202642321002PubTator, text miningPubMed

1 to 10 of 1,933

See all 1,933 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/368

GET https://conductscience.org/api/genes/v1/368/patents