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ITGAM: integrin subunit alpha M

1 protein, 66 patents, 1 drug, 0 trials, 22,697 NIH grants and 43,783 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolITGAMHGNC
Nameintegrin subunit alpha MHGNC
NCBI Gene ID3684NCBI Gene
HGNC IDHGNC:6149HGNC
EnsemblENSG00000169896NCBI Gene
AliasesCD11B, CD11b, CR3A, HNA-4, MAC-1, MAC1A, MO1A, SLEB6NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P11215Integrin alpha-M1,15231Ensembl, GeneID, HGNCUniProt

Patents 66

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026511370 A2026-04-142P11215Espacenet
JP 2026004568 A2026-01-1449981P11215Espacenet
KR 1020250166142 A2025-11-272P11215Espacenet
JP 2025537826 A2025-11-2014P11215Espacenet
EP 4650780 A22025-11-1916182P11215Espacenet
EP 4640849 A22025-10-293066P11215Espacenet
EP 4641201 A22025-10-2919725P11215Espacenet
EP 4641202 A22025-10-291107P11215Espacenet
EP 4641203 A22025-10-29627P11215Espacenet
JP 2025529142 A2025-09-042145P11215Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ROVELIZUMABCHEMBL2109224Integrin alpha-M/beta-2 antagonistANTAGONISTChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 22697

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2502,025NIH's project files
P30CA016672Cancer Center Support Grant1812,025NIH's project files
P30CA016058Cancer Center Support Grant812,025NIH's project files
P30CA091842Cancer Center Support Grant692,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program672,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support632,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant622,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award622,025NIH's project files
P30CA068485Cancer Center Support Grant612,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center582,025NIH's project files

Papers 43783

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822539PubTator, text miningPubMed
42819567PubTator, text miningPubMed
42816964PubTator, text miningPubMed
42815266PubTator, text miningPubMed
42798182PubTator, text miningPubMed
42797823PubTator, text miningPubMed
42791600PubTator, text miningPubMed
42791253PubTator, text miningPubMed
42784621PubTator, text miningPubMed
42781103PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license