Gene · 3691
ITGB4: integrin subunit beta 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ITGB4: integrin subunit beta 4. Genes, record 3691. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3691
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P16144 | Integrin beta-4 | 1,822 | 13 | Ensembl, GeneID, HGNC |
Source UniProt
Patents79
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 49984 | P16144 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 204 | P16144 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 173 | P16144 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2151 | P16144 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2151 | P16144 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 173 | P16144 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 204 | P16144 | Espacenet |
| US 12291562 B2 | 2025-05-06 | 11 | P16144 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 30095 | P16144 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 30095 | P16144 | Espacenet |
1 to 10 of 79
See all 79 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,117
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ITGB4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 22 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 15 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 8 | 2025 |
| ZIAAI000416 | Recombinant Virus Vaccines | 8 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 7 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 7 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 7 | 2025 |
| P30AI064518 | Center for AIDS Research | 6 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| UM1AI068614 | HIV Vaccines Clinical Trials Network Leadership and Operations Center | 6 | 2025 |
1 to 10 of 2,117Source NIH's project files
See all 2,117 nih grantsPapers3,577
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated bioinformatics identification and independent validation of FLNA, CCL2, and VMO1 as candidate biomarkers for dexamethasone-induced glaucoma. | Exp Eye Res | 2026 | 42810534 | PubTator, text mining | PubMed |
| Zeb1 Is a Determinant of EMT in Human MDA-MB-231 Breast Cancer Cells and M13-MDA231 Tumor Hybrids. | Int J Mol Sci | 2026 | 42794675 | PubTator, text mining | PubMed |
| ST6GAL1 promotes cancer stem-like cell-associated paclitaxel resistance through the EGFR-mTOR-SOX2/BMI1 axis in non-small cell lung cancer. | Cancer Drug Resist | 2026 | 42764906 | PubTator, text mining | PubMed |
| Circulating Serum AGRN and ADAMTS8 With Related Candidates as Potential Biomarkers for Carotid Plaque Presence and Vulnerability. | CNS Neurosci Ther | 2026 | 42747227 | PubTator, text mining | PubMed |
| Loss of ST8SIA6 is associated with enhanced MUC16-Integrin β4 signaling and aggressive phenotypes in colorectal cancer. | Biochem Biophys Rep | 2026 | 42698897 | PubTator, text mining | PubMed |
| A Multi-Layered Proteogenomic Framework for the Prioritization of Cell Surface Therapeutic Targets: Proof-of-Concept for Metastatic Colorectal Cancer. | Cancers (Basel) | 2026 | 42649884 | PubTator, text mining | PubMed |
| The TCN1 Paradox: Unraveling the Dual Role of Transcobalamin I in Colorectal Cancer-From Metabolic Regulation to Oncogenic Signaling. | Cancer Manag Res | 2026 | 42577958 | PubTator, text mining | PubMed |
| Generation and characterization of an anti ITGB4 monoclonal antibody that blocks Zika virus entry. | Front Immunol | 2026 | 42564182 | PubTator, text mining | PubMed |
| RETRACTION: Shear-Induced ITGB4 Promotes Endothelial Cell Inflammation and Atherosclerosis. | Oxid Med Cell Longev | 2026 | 42550461 | PubTator, text mining | PubMed |
| Transcriptomic Profiling of the Effects of DDR1 in Breast and Ovarian Cancer to Understand the Association Between DDR1 Expression and Patient Survival. | Genes (Basel) | 2026 | 42510800 | PubTator, text mining | PubMed |
1 to 10 of 3,577
See all 3,577 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3691
GET https://conductscience.org/api/genes/v1/3691/patents?page=2