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Gene · 3695

ITGB7: integrin subunit beta 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ITGB7: integrin subunit beta 7. Genes, record 3695. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3695

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Gene

Symbol
ITGB7
HGNC
Name
integrin subunit beta 7
HGNC
NCBI Gene ID
3695
NCBI Gene
HGNC ID
HGNC:6162
HGNC
Ensembl
ENSG00000139626
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P26010Integrin beta-77989Ensembl, GeneID, HGNC

Source UniProt

Patents119

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4724076 A22026-04-1573P26010Espacenet
WO 2026019692 A22026-01-22579P26010Espacenet
JP 2026004568 A2026-01-1449990P26010Espacenet
JP 2026004568 A2026-01-1449992P26010Espacenet
EP 4650780 A22025-11-192598P26010Espacenet
WO 2025228986 A12025-11-067P26010Espacenet
EP 4644537 A12025-11-057P26010Espacenet
JP 2025147176 A2025-10-067305P26010Espacenet
JP 2025147176 A2025-10-067306P26010Espacenet
JP 2025529142 A2025-09-042154P26010Espacenet

1 to 10 of 119

See all 119 patents

Drugs5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABRILUMABCHEMBL3137351Integrin alpha-4/beta-7 inhibitorINHIBITORChEMBL
ETROLIZUMABCHEMBL1743015Integrin beta-7 antagonistANTAGONISTChEMBL
FIRATEGRASTCHEMBL2104967Integrin alpha-4/beta-7 antagonistANTAGONISTChEMBL
NATALIZUMABCHEMBL1201607Integrin alpha-4/beta-7 inhibitorINHIBITORChEMBL
VEDOLIZUMABCHEMBL1743087Integrin alpha-4/beta-7 inhibitorINHIBITORChEMBL

Trials206

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants1,164

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleITGB7 papersNewest fiscal year
ZIAAI000887Role of HIV Envelope Proteins In Viral Replication and HIV Pathogenesis102025
U24AI126683Nonhuman Primate Reagent Resource52025
P30CA008748Cancer Center Support Grant42025
T32AI007306Immunologic Basis of Resistance and Hypersensitivity42025
UM1AI068635SDMC: HIV Vaccine Trials Network42025
D43TW005572International research training program in vaccine development and public health32025
P01CA155258Integrative Oncogenomics of Multiple Myeloma32025
P30AI064518Center for AIDS Research32025
P30CA014520UW Comprehensive Cancer Center Support32025
P30CA016058Cancer Center Support Grant32025

1 to 10 of 1,164Source NIH's project files

See all 1,164 nih grants

Papers1,437

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrin β7 induced by CB2R may not be confined to α4β7.Inflamm Bowel Dis202642758139PubTator, text miningPubMed
B-Cell Remodeling and Regulatory Phenotypes During Acute COVID-19 Are Unaffected by Polyclonal Anti-SARS-CoV-2 Antibody XAV-19.Eur J Immunol202642745635PubTator, text miningPubMed
MADCAM1 Gene Variants as Potential Pharmacogenomics Markers for Vedolizumab Response in Crohn's Disease Bio-Naïve Patients.Diagnostics (Basel)202642650926PubTator, text miningPubMed
The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy.Proc Natl Acad Sci U S A202642611989PubTator, text miningPubMed
Immunophenotype and proviral landscape of HTLV-1c infection and pulmonary disease.EBioMedicine202642492180PubTator, text miningPubMed
A single-cell atlas of ulcerative colitis reveals neutrophil-stromal circuits linked to biologic therapy resistance.Front Immunol202642367809PubTator, text miningPubMed
Unlocking new therapeutic horizons through integrative bioinformatics and transcriptomics for drug repositioning in breast cancer therapy.J Egypt Natl Canc Inst202642156642PubTator, text miningPubMed
Integrins in engraftment of ex vivo generated plasma cells.J Immunol202642096321PubTator, text miningPubMed
KLF2 overrides the resident memory CD8 T cell differentiation program, in opposition to KLF3.Proc Natl Acad Sci U S A202641871244PubTator, text miningPubMed
FBXO3-mediated DUSP9 ubiquitination promotes leukemia stem cell maintenance and tyrosine kinase inhibitor resistance in chronic myeloid leukemia.Cell Rep Med202641850237PubTator, text miningPubMed

1 to 10 of 1,437

See all 1,437 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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