Gene · 3704
ITPA: inosine triphosphatase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ITPA: inosine triphosphatase. Genes, record 3704. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3704
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9BY32 | Inosine triphosphate pyrophosphatase | 194 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 49791 | Q9BY32 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10271 | Q9BY32 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1552 | Q9BY32 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10579 | Q9BY32 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1552 | Q9BY32 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10579 | Q9BY32 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10271 | Q9BY32 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 40317 | Q9BY32 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 143288 | Q9BY32 | Espacenet |
| US 11047010 B2 | 2021-06-29 | 3062 | Q9BY32 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants875
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ITPA papers | Newest fiscal year |
|---|---|---|---|
| R01AI087856 | MECHANISM OF RNA SYNTHESIS BY DENGUE VIRUS NS5 | 5 | 2025 |
| R01AI094386 | Genome structure, transcription and packaging of dsRNA viruses | 5 | 2025 |
| R01GM071940 | High-Resolution CryoEM Reconstruction of Large Complexes | 5 | 2025 |
| ZIALM000061 | Finding Protein Sequence Motifs--Methods And Applications | 5 | 2025 |
| P30AI050409 | Center for AIDS Research at Emory University | 4 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 4 | 2025 |
| R01AI036040 | STRUCTURAL STUDIES ON ROTAVIRUS | 4 | 2025 |
| ZIAAI000897 | Noroviruses and Epidemic Gastroenteritis | 4 | 2025 |
| P20GM103427 | Nebraska Research Network in Functional Genomics | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
1 to 10 of 875Source NIH's project files
See all 875 nih grantsPapers2,079
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SAMD9/9L Innate Immunity: Antiviral Mechanisms and Evolutionary Trade-Offs of Multidomain Proteins. | Annu Rev Virol | 2026 | 42791213 | PubTator, text mining | PubMed |
| Flavivirus NS1 possesses NTPase and RNA helix unwinding activities. | Virol Sin | 2026 | 42753873 | PubTator, text mining | PubMed |
| Structure-based virtual screening leads to the discovery of a 4,5-dihydropyrazole derivative as the first dual inhibitor of West Nile virus NS3 helicase and protease. | Eur J Med Chem | 2026 | 42691700 | PubTator, text mining | PubMed |
| Genetic variants in purine metabolism and treatment resistance in schizophrenia: evidence supporting the adenosine hypothesis - a pilot study. | Front Pharmacol | 2026 | 42582614 | PubTator, text mining | PubMed |
| Guanylate kinase 1 is an enzyme responsible for inosine accumulation in RNA of mammalian cells deficient in inosine triphosphatase. | Proc Natl Acad Sci U S A | 2026 | 42531025 | PubTator, text mining | PubMed |
Genetic heterogeneity, movement disorders, and white matter abnormalities in pediatric developmental and epileptic encephalopathies: A retrospective cohort study from a National Neurodegenerative and Leukodystrophy Registry. | Epilepsy Res | 2026 | 42407302 | PubTator, text mining | PubMed |
| Stable inheritance of the Streptomyces linear plasmid SCP1 by dual ParABS partition systems. | Nucleic Acids Res | 2026 | 42258539 | PubTator, text mining | PubMed |
| Chikungunya virus nsP2: Insights into viral replication, pathogenesis, and therapeutic targeting. | Virulence | 2026 | 42178977 | PubTator, text mining | PubMed |
| Association of Variants in Candidate Pharmacogenes with Response to Mercaptopurine and Methotrexate in Pediatric Acute Lymphoblastic Leukemia: A Single-Center Experience from Croatia. | Oncol Ther | 2026 | 42168754 | PubTator, text mining | PubMed |
| Nuclease-NTPase antiphage defence systems use conserved molecular features to control bacterial immunity. | Nat Microbiol | 2026 | 42045369 | PubTator, text mining | PubMed |
1 to 10 of 2,079
See all 2,079 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3704
GET https://conductscience.org/api/genes/v1/3704/patents?page=2