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ITPR3: inositol 1,4,5-trisphosphate receptor type 3

1 protein, 42 patents, 0 drugs, 0 trials, 3,666 NIH grants and 6,014 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolITPR3HGNC
Nameinositol 1,4,5-trisphosphate receptor type 3HGNC
NCBI Gene ID3710NCBI Gene
HGNC IDHGNC:6182HGNC
EnsemblENSG00000096433NCBI Gene
AliasesCMT1J, IMD132, IMD133, IP3R, IP3R-3, IP3R3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q14573Inositol 1,4,5-trisphosphate-gated calcium channel ITPR32,67124Ensembl, GeneID, HGNCUniProt

Patents 42

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449805Q14573Espacenet
EP 4650780 A22025-11-199450Q14573Espacenet
EP 4641201 A22025-10-299703Q14573Espacenet
JP 2025529142 A2025-09-042161Q14573Espacenet
US 12371689 B22025-07-292161Q14573Espacenet
JP 2025517969 A2025-06-129703Q14573Espacenet
JP 2025517970 A2025-06-129450Q14573Espacenet
JP 2023123507 A2023-09-05334Q14573Espacenet
JP 2022141755 A2022-09-29247Q14573Espacenet
US 11446398 B22022-09-2040343Q14573Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3666

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DE014756Ca2+ and secretory dynamics in salivary acinar cells302,025NIH's project files
R01DE019245An experimental/computational approach for understanding salivary fluid secretion272,025NIH's project files
P30DK034989Yale Liver Center222,025NIH's project files
ZIADE000438Molecular Mechanisms Regulating Calcium Flux In Salivary Glands202,025NIH's project files
ZIADA000206Biological And Biochemical Characterization Of Sigma Receptors132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
P30CA016672Cancer Center Support Grant72,025NIH's project files
R01ES014901Molecular and Cellular Basis of PCB Developmental Neurotoxicity72,025NIH's project files
R35HL150778Ca2+ signaling Networks in Health and Disease72,025NIH's project files

Papers 6014

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42759460PubTator, text miningPubMed
42674123PubTator, text miningPubMed
42669372PubTator, text miningPubMed
42641287PubTator, text miningPubMed
42637755PubTator, text miningPubMed
42634536PubTator, text miningPubMed
42599297PubTator, text miningPubMed
42570836PubTator, text miningPubMed
42562338PubTator, text miningPubMed
42531130PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license