Gene · 375
ARF1: ARF GTPase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ARF1: ARF GTPase 1. Genes, record 375. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/375
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P84077 | ADP-ribosylation factor 1 | 181 | 40 | Ensembl, GeneID, HGNC |
Source UniProt
Patents82
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36757 | P84077 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 36758 | P84077 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 36759 | P84077 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2797 | P84077 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2797 | P84077 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3210 | P84077 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3211 | P84077 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3212 | P84077 | Espacenet |
| JP 2024100603 A | 2024-07-26 | 1 | P84077 | Espacenet |
| JP 2023064789 A | 2023-05-12 | 67 | P84077 | Espacenet |
1 to 10 of 82
See all 82 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,017
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ARF1 papers | Newest fiscal year |
|---|---|---|---|
| ZIABC007365 | Regulation of ADP-ribosylation factor | 35 | 2025 |
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 14 | 2025 |
| R37GM058615 | Mechanisms and Physiology of COPI Transport | 11 | 2025 |
| ZIAHD000196 | Phosphoinositide-calcium Signaling In Cell Regulation | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| R01GM083144 | Characterization of mammalian COG complex-interacting Golgi trafficking machinery | 6 | 2025 |
| R35GM136258 | GTPase Regulation of the Golgi Complex | 6 | 2025 |
| ZICHL006019 | Light Microscopy Core | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
1 to 10 of 2,017Source NIH's project files
See all 2,017 nih grantsPapers3,235
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The Microbial Metabolite IDA Sensitizes Tumor Cells to ARF1 Inhibition by Inducing SVIL-dependent Senescence. | Int J Biol Sci | 2026 | 42807340 | PubTator, text mining | PubMed |
| Lipids regulate export of lysosomal enzymes from the endoplasmic reticulum. | Proc Natl Acad Sci U S A | 2026 | 42752232 | PubTator, text mining | PubMed |
| Avl9 defines a family of DENN domain GTPase-activating proteins. | J Cell Biol | 2026 | 42714338 | PubTator, text mining | PubMed |
| IQSEC2 and ARF1 are involved in the development of the dentate gyrus. | Biochim Biophys Acta Gen Subj | 2026 | 42685987 | PubTator, text mining | PubMed |
| COPI Coatomer Regulates Several Steps of HDL Metabolism. | Arterioscler Thromb Vasc Biol | 2026 | 42592650 | PubTator, text mining | PubMed |
| Identification of gestational-age-dependent cell-free fetal mRNA transcriptional changes in human amniotic fluid. | J Hum Genet | 2026 | 42587014 | PubTator, text mining | PubMed |
| Virus-induced vesicular acidification enhances HIV immune evasion. | iScience | 2026 | 42541116 | PubTator, text mining | PubMed |
| Small molecules targeting ARF1 interaction with C9orf72:SMCR8:WDR41 complexes suppress its overactivation implicated in ALS/FTD. | bioRxiv | 2026 | 42427672 | PubTator, text mining | PubMed |
| ARMH3 acts as a central scaffold at the Golgi/TGN through interactions with Arl5, GBF1, and PI4KB. | J Biol Chem | 2026 | 42372921 | PubTator, text mining | PubMed |
| ADP-ribosylation factor 1 sustains regulatory T cell function and mucosal immune homeostasis in ulcerative colitis. | Mucosal Immunol | 2026 | 42349655 | PubTator, text mining | PubMed |
1 to 10 of 3,235
See all 3,235 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/375
GET https://conductscience.org/api/genes/v1/375/patents?page=2