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Gene · 375

ARF1: ARF GTPase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARF1: ARF GTPase 1. Genes, record 375. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/375

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Gene

Symbol
ARF1
HGNC
Name
ARF GTPase 1
HGNC
NCBI Gene ID
375
NCBI Gene
HGNC ID
HGNC:652
HGNC
Ensembl
ENSG00000143761
NCBI Gene
Aliases
PVNH8
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P84077ADP-ribosylation factor 118140Ensembl, GeneID, HGNC

Source UniProt

Patents82

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436757P84077Espacenet
JP 2026004568 A2026-01-1436758P84077Espacenet
JP 2026004568 A2026-01-1436759P84077Espacenet
EP 4650780 A22025-11-192797P84077Espacenet
JP 2025517970 A2025-06-122797P84077Espacenet
JP 2025062604 A2025-04-143210P84077Espacenet
JP 2025062604 A2025-04-143211P84077Espacenet
JP 2025062604 A2025-04-143212P84077Espacenet
JP 2024100603 A2024-07-261P84077Espacenet
JP 2023064789 A2023-05-1267P84077Espacenet

1 to 10 of 82

See all 82 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,017

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARF1 papersNewest fiscal year
ZIABC007365Regulation of ADP-ribosylation factor352025
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System142025
R37GM058615Mechanisms and Physiology of COPI Transport112025
ZIAHD000196Phosphoinositide-calcium Signaling In Cell Regulation92025
P30CA008748Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant82025
R01GM083144Characterization of mammalian COG complex-interacting Golgi trafficking machinery62025
R35GM136258GTPase Regulation of the Golgi Complex62025
ZICHL006019Light Microscopy Core62025
UL1TR001863Yale Clinical and Translational Science Award52025

1 to 10 of 2,017Source NIH's project files

See all 2,017 nih grants

Papers3,235

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The Microbial Metabolite IDA Sensitizes Tumor Cells to ARF1 Inhibition by Inducing SVIL-dependent Senescence.Int J Biol Sci202642807340PubTator, text miningPubMed
Lipids regulate export of lysosomal enzymes from the endoplasmic reticulum.Proc Natl Acad Sci U S A202642752232PubTator, text miningPubMed
Avl9 defines a family of DENN domain GTPase-activating proteins.J Cell Biol202642714338PubTator, text miningPubMed
IQSEC2 and ARF1 are involved in the development of the dentate gyrus.Biochim Biophys Acta Gen Subj202642685987PubTator, text miningPubMed
COPI Coatomer Regulates Several Steps of HDL Metabolism.Arterioscler Thromb Vasc Biol202642592650PubTator, text miningPubMed
Identification of gestational-age-dependent cell-free fetal mRNA transcriptional changes in human amniotic fluid.J Hum Genet202642587014PubTator, text miningPubMed
Virus-induced vesicular acidification enhances HIV immune evasion.iScience202642541116PubTator, text miningPubMed
Small molecules targeting ARF1 interaction with C9orf72:SMCR8:WDR41 complexes suppress its overactivation implicated in ALS/FTD.bioRxiv202642427672PubTator, text miningPubMed
ARMH3 acts as a central scaffold at the Golgi/TGN through interactions with Arl5, GBF1, and PI4KB.J Biol Chem202642372921PubTator, text miningPubMed
ADP-ribosylation factor 1 sustains regulatory T cell function and mucosal immune homeostasis in ulcerative colitis.Mucosal Immunol202642349655PubTator, text miningPubMed

1 to 10 of 3,235

See all 3,235 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/375

GET https://conductscience.org/api/genes/v1/375/patents?page=2