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Gene · 375790

AGRN: agrin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AGRN: agrin. Genes, record 375790. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/375790

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Gene

Symbol
AGRN
HGNC
Name
agrin
HGNC
NCBI Gene ID
375790
NCBI Gene
HGNC ID
HGNC:329
HGNC
Ensembl
ENSG00000188157
NCBI Gene
Aliases
AGRIN, CMS8, CMSPPD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00468Agrin2,0681Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026090543 A2026-06-02432O00468Espacenet
EP 4650780 A22025-11-1931843O00468Espacenet
JP 2025529142 A2025-09-04349O00468Espacenet
JP 2025529142 A2025-09-045435O00468Espacenet
EP 4606428 A22025-08-273O00468Espacenet
US 12371689 B22025-07-29349O00468Espacenet
US 12371689 B22025-07-295435O00468Espacenet
JP 2025517970 A2025-06-1231843O00468Espacenet
EP 4400164 A22024-07-174O00468Espacenet
JP 2024523001 A2024-06-25705O00468Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,943

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAGRN papersNewest fiscal year
R01AI114780Mechanisms of autoimmunity in myasthenia gravis102025
U54NS115054Rare Disease Network for Myasthenia Gravis82025
P30CA008748Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant72025
UL1TR001863Yale Clinical and Translational Science Award72025
P30CA016087Cancer Center Support Grant62025
P30CA014051Cancer Center Support (Core) Grant52025
P30EY003790Core Grant for Vision Research42025
R01CA097098Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer42025
P30AG028740University of Florida Older Americans Independence Center (OAIC)32025

1 to 10 of 1,943Source NIH's project files

See all 1,943 nih grants

Papers3,257

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Assay-specific reference intervals and evaluation of key preanalytical factors for C-terminal agrin fragment measured using the Abcam ab216945 ELISA.Clin Chim Acta202742648525PubTator, text miningPubMed
Ramadan fasting influences respiratory sarcopenia and plasma markers of neuromuscular junction health in older adults.Eur J Appl Physiol202642806069PubTator, text miningPubMed
Crk/Crk-L-mediated Rapgef1 recruitment couples MuSK signaling to AChR anchoring at the neuromuscular junction.Cell Chem Biol202642772281PubTator, text miningPubMed
Ultrasound-Derived Quadriceps Muscle Measurements Are Independently Associated With Physical Frailty in Patients Undergoing Hemodialysis.J Ren Nutr202642767388PubTator, text miningPubMed
Circulating Serum AGRN and ADAMTS8 With Related Candidates as Potential Biomarkers for Carotid Plaque Presence and Vulnerability.CNS Neurosci Ther202642747227PubTator, text miningPubMed
AGRN activates GPX4 via the Wnt/beta-catenin signaling pathway to suppress ferroptosis in cervical cancer cells.Brief Funct Genomics202642742282PubTator, text miningPubMed
Protein mediators of chronic kidney disease in Type 2 diabetes: A mendelian randomization study.PLoS Med202642726788PubTator, text miningPubMed
NMJ-associated transcriptomic remodeling correlates with disease severity in juvenile dermatomyositis.Inflamm Res202642700229PubTator, text miningPubMed
Targeting RhoA/ROCK Signaling to Modulate Extracellular Matrix Remodeling in Corneal Endothelial Dystrophies.Invest Ophthalmol Vis Sci202642593179PubTator, text miningPubMed
MuSK myasthenia gravis: from antigen-antibody to clinical translation.Front Immunol202642582756PubTator, text miningPubMed

1 to 10 of 3,257

See all 3,257 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/375790

GET https://conductscience.org/api/genes/v1/375790/patents