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Gene · 3782

KCNN3: potassium calcium-activated channel subfamily N member 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KCNN3: potassium calcium-activated channel subfamily N member 3. Genes, record 3782. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3782

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Gene

Symbol
KCNN3
HGNC
Name
potassium calcium-activated channel subfamily N member 3
HGNC
NCBI Gene ID
3782
NCBI Gene
HGNC ID
HGNC:6292
HGNC
Ensembl
ENSG00000143603
NCBI Gene
Aliases
KCa2.3, SK3, SKCA3, ZLS3, hSK3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UGI6Small conductance calcium-activated potassium channel protein 37310Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458626Q9UGI6Espacenet
EP 4641201 A22025-10-292361Q9UGI6Espacenet
JP 2025529142 A2025-09-042257Q9UGI6Espacenet
US 12371689 B22025-07-292257Q9UGI6Espacenet
JP 2025517969 A2025-06-122361Q9UGI6Espacenet
JP 2025032204 A2025-03-1130442Q9UGI6Espacenet
EP 4461818 A22024-11-1330442Q9UGI6Espacenet
JP 2024112982 A2024-08-214588Q9UGI6Espacenet
JP 2023058610 A2023-04-2530442Q9UGI6Espacenet
JP 2022184996 A2022-12-134588Q9UGI6Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,060

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKCNN3 papersNewest fiscal year
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL232025
R01HL085844Functional interactions of cardiac ion channels82025
T32HL086350Training Program in Basic and Translational Cardiovascular Science62025
ZIAHL006001Framingham Project/Levy62025
P30CA008748Cancer Center Support Grant52025
P30DK063491Diabetes Research Center (DRC)52025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal52025
P30CA016672Cancer Center Support Grant42025
P30ES005605Environmental Health Sciences Research Center42025
R01HL128831Vascular Dysfunction in Myocardial Ischemia and Metabolic Syndrome42025

1 to 10 of 1,060Source NIH's project files

See all 1,060 nih grants

Papers1,373

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated Transcriptomic and Machine Learning Analyses Identify KCNN3 and TLR10 as Candidate Cell-Type-Associated Molecules in Idiopathic Membranous Nephropathy.Int J Gen Med202642801211PubTator, text miningPubMed
Functional recruitment and regulatory mechanisms of SK channels in patients with early stages of ventricular remodeling.J Mol Cell Cardiol202642413689PubTator, text miningPubMed
Phylogeny of SK channels and functional characterization of the conserved Phe in the S3-S4 loop.Biophys J202642357870PubTator, text miningPubMed
Dysregulation of neurodevelopmental regulatory networks in Anorexia Nervosa: an integrated multi-layered omics analysis.Front Cell Dev Biol202642238894PubTator, text miningPubMed
Integrative transcriptomic analysis revealed the roles and prognostic value of ion channels in hypertrophic cardiomyopathy.Front Pharmacol202642158954PubTator, text miningPubMed
A Ponatinib-Associated Transcriptomic Signature: Implications for Cardiovascular Toxicity.Int J Mol Sci202642123636PubTator, text miningPubMed
SPOP-mediated K27-linked non-degradative ubiquitination of KCNN3 suppressing HCC progression via the CTCF-SATB1 axis.Cell Death Dis202642106340PubTator, text miningPubMed
Predictive model for clear cell renal cell carcinoma: a novel model integrating sunitinib resistance and prognosis related genes and clinical factors.Clin Transl Oncol202642020680PubTator, text miningPubMed
Programmed cell death: a promising management for Alzheimer's disease.Apoptosis202641904723PubTator, text miningPubMed
The dynamics of podosomes, extracellular matrix-associated proteins regulate the cytoskeletal remodeling, mechanosensing, migration in Tau.Adv Protein Chem Struct Biol202641904004PubTator, text miningPubMed

1 to 10 of 1,373

See all 1,373 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3782

GET https://conductscience.org/api/genes/v1/3782/patents?page=2