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KCNN4: potassium calcium-activated channel subfamily N member 4
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Gene · 3783

Papers2,742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,742

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TitleJournalYearPMIDFound bySource
Local targeted suppression of neocortical spreading depolarization amplitude by viral expression of KCa3.1 channels.Gene Ther202642811097PubTator, text miningPubMed
Small-Molecule NANT Therapeutics Targeting the Brain-Immune Axis in Alzheimer's Disease: Mechanisms, Clinical Progress, and Translational Challenges.Molecules202642796561PubTator, text miningPubMed
Potassium channels as an ionic checkpoint in tumor immunity.Front Pharmacol202642787526PubTator, text miningPubMed
The cornea-trigeminal axis: potassium channels as master regulators of ocular surface homeostasis and sensory transduction.Front Cell Dev Biol202642707580PubTator, text miningPubMed
Effect of glabridin on ion transport across primary human bronchial epithelial cells.Am J Physiol Cell Physiol202642686216PubTator, text miningPubMed
Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart.J Precis Med (Amst)202642644057PubTator, text miningPubMed
Mechanical force activates KCNN4 to regulate the NLRP3 inflammasome in periodontal ligament cells during orthodontic tooth movement.J Adv Res202642628920PubTator, text miningPubMed
Sub-millivolt voltage imaging reveals gap junction-mediated bioelectric contact inhibition.Nat Commun202642603816PubTator, text miningPubMed
Targeting FOSL1-KCa3.1 inhibits ferroptosis and cartilage destruction by suppressing mitochondrial hyperfusion.Acta Pharmacol Sin202642552470PubTator, text miningPubMed
Recurrent KCNN4 p.Ser314Pro variant in a child with Gardos channelopathy: a 6-year follow-up.Blood Cells Mol Dis202642546370PubTator, text miningPubMed
Mutation-Induced Pocket Deactivation: How Ser353/Pro245 Alters KCa2.2 vs. KCa3.1 Ligand Selectivity.Arch Pharm (Weinheim)202642458866PubTator, text miningPubMed
Integrating network toxicology and in vitro validation to elucidate PET microplastic-induced osteoarthritis pathogenesis.Front Pharmacol202642453583PubTator, text miningPubMed
Comparative Interactome Analysis Reveals Architectural Principles Governing K+ Channel Function in Cancer.Int J Mol Sci202642450133PubTator, text miningPubMed
Integrated Metabolomic and Transcriptomic Profiling Reveals a Distinct Pathological Aging State in Diminished Ovarian Reserve of Advanced Reproductive-Age Women.Reprod Sci202642426427PubTator, text miningPubMed
Uncovering subtype-selective activation of the KCa3.1 channel by SKA-111.Structure202642392030PubTator, text miningPubMed
Severe anemia in a fetal case of dehydrated hereditary stomatocytosis caused by a KCNN4 variant identified by routine second trimester ultrasound.Taiwan J Obstet Gynecol202642362277PubTator, text miningPubMed
Phylogeny of SK channels and functional characterization of the conserved Phe in the S3-S4 loop.Biophys J202642357870PubTator, text miningPubMed
Identifying diagnostic markers and constructing a prognostic model for pancreatic cancer based on microarray and bioinformatic analysis.Discov Oncol202642329507PubTator, text miningPubMed
Integrated bulk and single-cell RNA sequencing reveals a prognostic neuro-mimicry signature in papillary thyroid carcinoma.Discov Oncol202642329337PubTator, text miningPubMed
Senicapoc in Patients with Idiopathic Pulmonary Fibrosis or Other Progressive Fibrotic Interstitial Lung Diseases: Protocol for a Randomised, Double-Blind, Placebo-Controlled, Multicentre Phase II Trial.
Diagnostics (Basel)202642279523PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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