Gene · 379
ARL4D: ARF like GTPase 4D
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ARL4D: ARF like GTPase 4D. Genes, record 379. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/379
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P49703 | ADP-ribosylation factor-like protein 4D | 201 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents13
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36802 | P49703 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5448 | P49703 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5448 | P49703 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3380 | P49703 | Espacenet |
| JP 2022147356 A | 2022-10-06 | 308 | P49703 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 3380 | P49703 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 106351 | P49703 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 771 | P49703 | Espacenet |
| JP 2019158777 A | 2019-09-19 | 952 | P49703 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 217237 | P49703 | Espacenet |
1 to 10 of 13
See all 13 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants236
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ARL4D papers | Newest fiscal year |
|---|---|---|---|
| P30CA016086 | Cancer Center Support Grant | 2 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 2 | 2025 |
| R01AG050986 | Higher Order Chromatin and Genetic Risk for Alzheimer's Disease | 2 | 2025 |
| R01CA268179 | Functional interplay between Hippo and estrogen receptor ESR1 | 2 | 2025 |
| ZICES102445 | Gene Expression and Microarrays | 2 | 2025 |
| K12HD000850 | Pediatric Scientist Development Program | 1 | 2025 |
| K12HD052892 | Molecular Basis of Pediatric Disease | 1 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 1 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 1 | 2025 |
| P01CA234228 | APOBEC Mutagenesis in Cancer | 1 | 2025 |
1 to 10 of 236Source NIH's project files
See all 236 nih grantsPapers218
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Single-Cell Landscape Change in Cervical Epithelial Cells and Microenvironment During the Transformation from CINIII to Cervical Squamous Cell Carcinoma. | Cancers (Basel) | 2026 | 42193032 | PubTator, text mining | PubMed |
| Utilising Machine Learning and Single-Cell Analysis to Uncover SKCM Metastasis-Related Genes. | IET Syst Biol | 2026 | 41961982 | PubTator, text mining | PubMed |
| Phosphatidylinositol 4,5-bisphosphate mediates Arl4D self-interaction to promote Pak1 signaling. | Proc Natl Acad Sci U S A | 2026 | 41779780 | PubTator, text mining | PubMed |
| TBC1D15 functions as an Arl4D GAP and promotes the mitochondrial translocation of Arl4D for organelle homeostasis. | J Cell Sci | 2026 | 41709823 | PubTator, text mining | PubMed |
| The phosphorylation of Pak1 by Erk1/2 to drive cell migration requires Arl4D acting as a scaffolding protein. | J Cell Sci | 2025 | 40309925 | PubTator, text mining | PubMed |
| Integration of CRISPR/dCas9-Based methylation editing with guide positioning sequencing identifies dynamic changes of mrDEGs in breast cancer progression. | Cell Mol Life Sci | 2025 | 39833630 | PubTator, text mining | PubMed |
| Exploring novel drug targets for erectile dysfunction through plasma proteome with genome. | Sex Med | 2024 | 39790564 | PubTator, text mining | PubMed |
| Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways. | J Cell Sci | 2024 | 38606629 | PubTator, text mining | PubMed |
| Epigenetics of prenatal stress in humans: the current research landscape. | Clin Epigenetics | 2024 | 38308342 | PubTator, text mining | PubMed |
| Sox9 regulates alternative splicing and pancreatic beta cell function. | Nat Commun | 2024 | 38238288 | PubTator, text mining | PubMed |
1 to 10 of 218
See all 218 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/379
GET https://conductscience.org/api/genes/v1/379/patents