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KIR2DL4: killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4

1 protein, 19 patents, 0 drugs, 0 trials, 3,852 NIH grants and 8,276 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolKIR2DL4HGNC
Namekiller cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4HGNC
NCBI Gene ID3805NCBI Gene
HGNC IDHGNC:6332HGNC
EnsemblENSG00000189013NCBI Gene
Aliases103AS, 15.212, CD158D, G9P, KIR-103AS, KIR-2DL4, KIR103, KIR103ASNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q99706Killer cell immunoglobulin-like receptor 2DL43771Ensembl, GeneID, HGNCUniProt

Patents 19

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1968977Q99706Espacenet
JP 2025529142 A2025-09-042299Q99706Espacenet
JP 2025529142 A2025-09-046814Q99706Espacenet
US 12371689 B22025-07-292299Q99706Espacenet
US 12371689 B22025-07-296814Q99706Espacenet
JP 2025517970 A2025-06-1268977Q99706Espacenet
JP 2024528077 A2024-07-2610Q99706Espacenet
EP 4378952 A12024-06-0510Q99706Espacenet
KR 1020240042483 A2024-04-0210Q99706Espacenet
JP 2024504875 A2024-02-0110Q99706Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3852

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA111412NK cells, their receptors and cancer therapy622,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies572,025NIH's project files
P30CA008748Cancer Center Support Grant552,025NIH's project files
P30CA016672Cancer Center Support Grant402,025NIH's project files
ZIABC010791Effects of genetic polymorphism in MHC, KIR, and related loci on human disease342,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)322,025NIH's project files
T32AI007290Molecular and Cellular Immunobiology312,025NIH's project files
U24CA076518A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research312,025NIH's project files
U01AI090905Insights Into Immune-Related Diseases Born from Population Genomics302,025NIH's project files
U01AI069197Hematopoietic Stem Cell And Cord Blood Transplantation282,025NIH's project files

Papers 8276

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823801PubTator, text miningPubMed
42817165PubTator, text miningPubMed
42815159PubTator, text miningPubMed
42814514PubTator, text miningPubMed
42806401PubTator, text miningPubMed
42777954PubTator, text miningPubMed
42757130PubTator, text miningPubMed
42747971PubTator, text miningPubMed
42731183PubTator, text miningPubMed
42702363PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license