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Gene · 3806

KIR2DS1: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KIR2DS1: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1. Genes, record 3806. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3806

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Gene

Symbol
KIR2DS1
HGNC
Name
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
HGNC
NCBI Gene ID
3806
NCBI Gene
HGNC ID
HGNC:6333
HGNC
Ensembl
ENSG00000276387
NCBI Gene
Aliases
CD158H, CD158a, EB6ActI, EB6ActII, p50.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14954Killer cell immunoglobulin-like receptor 2DS13040GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2024528077 A2024-07-2611Q14954Espacenet
EP 4378952 A12024-06-0511Q14954Espacenet
KR 1020240042483 A2024-04-0211Q14954Espacenet
JP 2024504875 A2024-02-0111Q14954Espacenet
KR 1020230152035 A2023-11-0211Q14954Espacenet
US 11446398 B22022-09-2044034Q14954Espacenet
US 11446398 B22022-09-2044039Q14954Espacenet
US 11446398 B22022-09-2044040Q14954Espacenet
US 11446398 B22022-09-2044041Q14954Espacenet
US 11446398 B22022-09-2044042Q14954Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants700

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKIR2DS1 papersNewest fiscal year
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies202025
P01CA111412NK cells, their receptors and cancer therapy192025
P30CA008748Cancer Center Support Grant192025
U01AI090905Insights Into Immune-Related Diseases Born from Population Genomics182025
U01AI069197Hematopoietic Stem Cell And Cord Blood Transplantation152025
P30CA077598Cancer Center Support Grant132025
U24CA076518A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research122025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant112025
ZIABC010791Effects of genetic polymorphism in MHC, KIR, and related loci on human disease112025
T32AI007290Molecular and Cellular Immunobiology92025

1 to 10 of 700Source NIH's project files

See all 700 nih grants

Papers1,400

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
KIR genes influence endometrial dysbiosis, chronic endometritis and antibiotic response in infertile women.Reprod Biomed Online202642476044PubTator, text miningPubMed
Flow Cytometric Detection of NK Cell KIR Receptors: a Novel Tool for Functional Profiling in Reproductive Failure.Clin Lab202642411671PubTator, text miningPubMed
Outcomes of PTCY-Based Haploidentical Transplants and Donor Factors Affecting Outcomes: A 12-year Experience from India.Blood Cell Ther202642253351PubTator, text miningPubMed
Examining the association between fetal HLA-C, maternal KIR haplotypes and birth weight.PLoS Genet202642008539PubTator, text miningPubMed
Molecular and endocrine differences in early miscarriage associated with KIR polymorphisms in European ancestry women.Reprod Biomed Online202641980565PubTator, text miningPubMed
Benralizumab reduces sputum ANCA in patients with eosinophilic granulomatosis with polyangiitis.ERJ Open Res202641809856PubTator, text miningPubMed
Integrative Roles of NK Receptors and γδ TCRs in γδ T Cell-Mediated Cancer Immunity.Immune Netw202641800030PubTator, text miningPubMed
Mechanisms of tumor cell evasion from NK cell-mediated killing and advances in NK cell-based cancer immunotherapy.Pharm Sci Adv202641799416PubTator, text miningPubMed
Establishment and Multidimensional Characterization of a Novel Epstein-Barr Virus (EBV)-Negative Human Type I Natural Killer T-Cell Line NKT617.Lab Invest202641308748PubTator, text miningPubMed
Shedding light on the complicated world of alloreactive NK cells.Haematologica202641230700PubTator, text miningPubMed

1 to 10 of 1,400

See all 1,400 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3806

GET https://conductscience.org/api/genes/v1/3806/patents?page=2