Gene · 3811
KIR3DL1: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KIR3DL1: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1. Genes, record 3811. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3811
On this page
Gene
- Aliases
- AMB11, CD158E1, CD158e1/2, CD158e2, KIR, KIR3DL1/S1, NKAT-3, NKAT3, NKB1, NKB1B, cl-11, cl-2, nkat3
- NCBI Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P43629 | Killer cell immunoglobulin-like receptor 3DL1 | 444 | 18 | Ensembl, GeneID, HGNC |
Source UniProt
Patents54
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 50734 | P43629 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50736 | P43629 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10843 | P43629 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2300 | P43629 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2300 | P43629 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10843 | P43629 | Espacenet |
| US 12152253 B2 | 2024-11-26 | 3 | P43629 | Espacenet |
| JP 2024513880 A | 2024-03-27 | 30 | P43629 | Espacenet |
| US 11858990 B2 | 2024-01-02 | 169 | P43629 | Espacenet |
| KR 1020230165913 A | 2023-12-05 | 30 | P43629 | Espacenet |
1 to 10 of 54
See all 54 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,371
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KIR3DL1 papers | Newest fiscal year |
|---|---|---|---|
| P01CA111412 | NK cells, their receptors and cancer therapy | 39 | 2025 |
| ZIABC010791 | Effects of genetic polymorphism in MHC, KIR, and related loci on human disease | 31 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 29 | 2025 |
| P01CA065493 | Off-the-Shelf Immune Effector Cells for Hematological Malignancies | 26 | 2025 |
| U01AI090905 | Insights Into Immune-Related Diseases Born from Population Genomics | 24 | 2025 |
| U01AI069197 | Hematopoietic Stem Cell And Cord Blood Transplantation | 21 | 2025 |
| T32AI007290 | Molecular and Cellular Immunobiology | 20 | 2025 |
| P30CA077598 | Cancer Center Support Grant | 17 | 2025 |
| ZIABC010792 | Molecular genetics and population studies of the KIR and HLA gene complexes | 17 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 14 | 2025 |
1 to 10 of 1,371Source NIH's project files
See all 1,371 nih grantsPapers2,526
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Clusterin expression and germinal center morphometry help distinguish idiopathic multicentric castleman disease from select lymphadenopathies. | Front Immunol | 2026 | 42824315 | PubTator, text mining | PubMed |
| Do FLT3 and KIR3DL1 converge on a common immune surveillance axis in treatment-free remission of chronic myeloid leukemia? | Leukemia | 2026 | 42587024 | PubTator, text mining | PubMed |
| High KIR diversity in Uganda and Botswana children living with HIV. | Hum Immunol | 2026 | 42320219 | PubTator, text mining | PubMed |
| Combos New and Old Counter PD-(L)1 Resistance, Treat Rare Cancers. | Cancer Discov | 2026 | 42240229 | PubTator, text mining | PubMed |
| Activating KIR3DS1: A key driver of KIR3DL1/HLA-Bw4-linked risk in CML. | Hum Immunol | 2026 | 42034883 | PubTator, text mining | PubMed |
| Long-read KIR genotyping reveals donor KIR/HLA polymorphisms linked to posttransplant relapse in T-cell malignancies. | Blood Adv | 2026 | 41995743 | PubTator, text mining | PubMed |
| Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia. | Leukemia | 2026 | 41888396 | PubTator, text mining | PubMed |
| A Composite interaction Score: Prioritizing cell-cell interactions from single-cell RNA-seq with application to pre-menopausal epithelial barriers. | J Adv Res | 2026 | 41875947 | PubTator, text mining | PubMed |
| A genetic study of immunity in depression and interactions with childhood maltreatment. | Transl Psychiatry | 2026 | 41856978 | PubTator, text mining | PubMed |
| Thymosin α1-induced secretion of the IL-15/RA complex by THP-1-derived dendritic cells restrains HIV latency in vitro. | Virulence | 2026 | 41824632 | PubTator, text mining | PubMed |
1 to 10 of 2,526
See all 2,526 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3811
GET https://conductscience.org/api/genes/v1/3811/patents?page=2