Gene · 3814
KISS1: KiSS-1 metastasis suppressor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KISS1: KiSS-1 metastasis suppressor. Genes, record 3814. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3814
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15726 | Metastasis-suppressor KiSS-1 | 138 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents38
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026017877 A1 | 2026-01-22 | 12 | Q15726 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8184 | Q15726 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 7479 | Q15726 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6816 | Q15726 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6816 | Q15726 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8184 | Q15726 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 7479 | Q15726 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 7479 | Q15726 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6756 | Q15726 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 7486 | Q15726 | Espacenet |
1 to 10 of 38
See all 38 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants876
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KISS1 papers | Newest fiscal year |
|---|---|---|---|
| P51OD011092 | Support for National Primate Research Center | 24 | 2025 |
| T32HD007203 | Training in Reproductive Sciences | 17 | 2025 |
| P30CA168524 | The University of Kansas Cancer Center | 15 | 2025 |
| R01HD082314 | Deciphering the functional role of MKRN3 in puberty and reproduction | 15 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 9 | 2025 |
| P51OD011106 | Wisconsin National Primate Research Center Support | 7 | 2025 |
| T32DK007529 | Training Grant in Academic Endocrinology | 7 | 2025 |
| P20GM103418 | Kansas IDeA Network of Biomedical Research Excellence 5 | 4 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 876Source NIH's project files
See all 876 nih grantsPapers2,309
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus? | Int J Mol Sci | 2026 | 42794587 | PubTator, text mining | PubMed |
| RETRACTION: Up-regulation of KISS1 as a Novel Target of Let-7i in Melanoma Serves as a Potential Suppressor of Migration and Proliferation In Vitro. | J Cell Mol Med | 2026 | 42708619 | PubTator, text mining | PubMed |
| Follicular kisspeptin-VEGF axis in polycystic ovary syndrome and ovarian hyperstimulation syndrome. | J Assist Reprod Genet | 2026 | 42663893 | PubTator, text mining | PubMed |
| Effect of High Intensity Sweeteners on the Reproductive System: From the Onset of Puberty to Menstrual Health: A Comprehensive Review of Human and Animal Evidence. | Int J Womens Health | 2026 | 42657207 | PubTator, text mining | PubMed |
| Seminal Plasma Kisspeptin-1 and Kisspeptin-54 Levels Are Associated With Semen Parameters and Oxidative Stress in Male Infertility. | Clin Endocrinol (Oxf) | 2026 | 42566672 | PubTator, text mining | PubMed |
| Precocious puberty in boys: current insights into etiology, genetic advances, and environmental factors. | Front Endocrinol (Lausanne) | 2026 | 42534783 | PubTator, text mining | PubMed |
| Progesterone-KISS1 axis impairs amniotic epithelial cell function and promotes premature rupture of membranes. | Placenta | 2026 | 42385385 | PubTator, text mining | PubMed |
| Erratum. | Neuroendocrinology | 2026 | 42378175 | PubTator, text mining | PubMed |
| Kisspeptin as a Precision Biomarker in Personalized Pharmacy: Implications for Individualized Monitoring of Early Pregnancy Viability. | Pharmacy (Basel) | 2026 | 42347060 | PubTator, text mining | PubMed |
| Exogenous Kisspeptin-10 inhibits ovarian cancer progression through targeting the SP1-hTERT-ZEB1 regulatory axis. | Cytotechnology | 2026 | 42292313 | PubTator, text mining | PubMed |
1 to 10 of 2,309
See all 2,309 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3814
GET https://conductscience.org/api/genes/v1/3814/patents?page=2