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Gene · 3814

KISS1: KiSS-1 metastasis suppressor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KISS1: KiSS-1 metastasis suppressor. Genes, record 3814. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3814

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Gene

Symbol
KISS1
HGNC
Name
KiSS-1 metastasis suppressor
HGNC
NCBI Gene ID
3814
NCBI Gene
HGNC ID
HGNC:6341
HGNC
Ensembl
ENSG00000170498
NCBI Gene
Aliases
HH13, KiSS-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15726Metastasis-suppressor KiSS-11382Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026017877 A12026-01-2212Q15726Espacenet
EP 4650780 A22025-11-198184Q15726Espacenet
JP 2025147176 A2025-10-067479Q15726Espacenet
JP 2025529142 A2025-09-046816Q15726Espacenet
US 12371689 B22025-07-296816Q15726Espacenet
JP 2025517970 A2025-06-128184Q15726Espacenet
JP 2025028160 A2025-02-287479Q15726Espacenet
KR 1020250010750 A2025-01-217479Q15726Espacenet
JP 2024123008 A2024-09-106756Q15726Espacenet
JP 2024109657 A2024-08-147486Q15726Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants876

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKISS1 papersNewest fiscal year
P51OD011092Support for National Primate Research Center242025
T32HD007203Training in Reproductive Sciences172025
P30CA168524The University of Kansas Cancer Center152025
R01HD082314Deciphering the functional role of MKRN3 in puberty and reproduction152025
P30DK063491Diabetes Research Center (DRC)92025
P51OD011106Wisconsin National Primate Research Center Support72025
T32DK007529Training Grant in Academic Endocrinology72025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 542025
P30CA013148Comprehensive Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025

1 to 10 of 876Source NIH's project files

See all 876 nih grants

Papers2,309

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus?Int J Mol Sci202642794587PubTator, text miningPubMed
RETRACTION: Up-regulation of KISS1 as a Novel Target of Let-7i in Melanoma Serves as a Potential Suppressor of Migration and Proliferation In Vitro.J Cell Mol Med202642708619PubTator, text miningPubMed
Follicular kisspeptin-VEGF axis in polycystic ovary syndrome and ovarian hyperstimulation syndrome.J Assist Reprod Genet202642663893PubTator, text miningPubMed
Effect of High Intensity Sweeteners on the Reproductive System: From the Onset of Puberty to Menstrual Health: A Comprehensive Review of Human and Animal Evidence.Int J Womens Health202642657207PubTator, text miningPubMed
Seminal Plasma Kisspeptin-1 and Kisspeptin-54 Levels Are Associated With Semen Parameters and Oxidative Stress in Male Infertility.Clin Endocrinol (Oxf)202642566672PubTator, text miningPubMed
Precocious puberty in boys: current insights into etiology, genetic advances, and environmental factors.Front Endocrinol (Lausanne)202642534783PubTator, text miningPubMed
Progesterone-KISS1 axis impairs amniotic epithelial cell function and promotes premature rupture of membranes.Placenta202642385385PubTator, text miningPubMed
Erratum.Neuroendocrinology202642378175PubTator, text miningPubMed
Kisspeptin as a Precision Biomarker in Personalized Pharmacy: Implications for Individualized Monitoring of Early Pregnancy Viability.Pharmacy (Basel)202642347060PubTator, text miningPubMed
Exogenous Kisspeptin-10 inhibits ovarian cancer progression through targeting the SP1-hTERT-ZEB1 regulatory axis.Cytotechnology202642292313PubTator, text miningPubMed

1 to 10 of 2,309

See all 2,309 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3814

GET https://conductscience.org/api/genes/v1/3814/patents?page=2