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Gene · 3817

KLK2: kallikrein related peptidase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KLK2: kallikrein related peptidase 2. Genes, record 3817. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3817

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Gene

Symbol
KLK2
HGNC
Name
kallikrein related peptidase 2
HGNC
NCBI Gene ID
3817
NCBI Gene
HGNC ID
HGNC:6363
HGNC
Ensembl
ENSG00000167751
NCBI Gene
Aliases
KLK2A2, hGK-1, hK2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P20151Kallikrein-22612Ensembl, GeneID, HGNC

Source UniProt

Patents157

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026222432 A12026-10-2262P20151Espacenet
WO 2026222444 A12026-10-223P20151Espacenet
JP 2026090241 A2026-06-0247P20151Espacenet
EP 4741015 A22026-05-137P20151Espacenet
JP 2026064989 A2026-04-1462P20151Espacenet
JP 2026004568 A2026-01-1450558P20151Espacenet
EP 4650780 A22025-11-194912P20151Espacenet
JP 2025147176 A2025-10-067534P20151Espacenet
JP 2025529142 A2025-09-046826P20151Espacenet
US 12371689 B22025-07-296826P20151Espacenet

1 to 10 of 157

See all 157 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,083

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKLK2 papersNewest fiscal year
P50CA092629SPORE in Prostate Cancer852025
P30CA008748Cancer Center Support Grant592025
P50CA097186The Pacific Northwest Prostate Cancer SPORE192025
P30CA016056Roswell Park Cancer Center Support Grant182025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer172025
P30CA006973Regional Oncology Research Center172025
P50CA186786Michigan Prostate SPORE 2025-203092025
P30CA016042Cancer Center Support Grant82025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center82025
P50CA180995SPORE in Prostate Cancer82025

1 to 10 of 1,083Source NIH's project files

See all 1,083 nih grants

Papers1,753

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Bifunctional covalent organic framework for rapid isolation of extracellular vesicles and proteomics-based biomarker discovery.Talanta202742391702PubTator, text miningPubMed
Fe3O4-Au cluster-satellite particles as direct colorimetric reporters in a smartphone-quantified lateral flow immunoassay for prostate-specific antigen.Mikrochim Acta202642789117PubTator, text miningPubMed
Artificial neural network engineering of high carrier mobility single-layer graphene interfaces for ultrasensitive FET-aptasensors in clinical PSA detection.Biosens Bioelectron202642659930PubTator, text miningPubMed
Expression patterns of potential targets for antibody-directed therapy in metastatic castration-resistant prostate cancer patients.Eur J Cancer202642623835PubTator, text miningPubMed
Targeting human kallikrein 2 in prostate cancer.Clin Adv Hematol Oncol202642283714PubTator, text miningPubMed
Integrative Surface Antigen Profiling of KLK2 and STEAP1 in Advanced Prostate Cancer.Mol Cancer Res202642189191PubTator, text miningPubMed
Evaluation of Tissue from Patients with Prostate Cancer Identifies B7-H3 as an Androgen-Regulated, Broadly Expressed, Combinatorial Therapeutic Target.Clin Cancer Res202642053993PubTator, text miningPubMed
Spatial Robustness of Prostate Cancer Biomarkers Evaluated by Spatial Transcriptomics.Prostate202641911496PubTator, text miningPubMed
Estimating the Effect of Finasteride on Kallikrein Marker Levels in Blood and the Use of Converted Markers in the Four-Kallikrein Model.Eur Urol Focus202641864782PubTator, text miningPubMed
Editorial Comment on Beyond Total PSA: Clinical Significance of S2,3PSA% in Reducing Unnecessary Prostate Biopsies.Int J Urol202641837352PubTator, text miningPubMed

1 to 10 of 1,753

See all 1,753 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3817

GET https://conductscience.org/api/genes/v1/3817/patents?page=2