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Gene · 382

ARF6: ARF GTPase 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARF6: ARF GTPase 6. Genes, record 382. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/382

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Gene

Symbol
ARF6
HGNC
Name
ARF GTPase 6
HGNC
NCBI Gene ID
382
NCBI Gene
HGNC ID
HGNC:659
HGNC
Ensembl
ENSG00000165527
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62330ADP-ribosylation factor 617520Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193875P62330Espacenet
JP 2025517970 A2025-06-123875P62330Espacenet
JP 2025062604 A2025-04-143227P62330Espacenet
EP 4484957 A12025-01-019P62330Espacenet
JP 2024123008 A2024-09-104790P62330Espacenet
WO 2023162878 A2023-08-319P62330Espacenet
JP 2023064789 A2023-05-1273P62330Espacenet
WO 2023074712 A2023-05-0419P62330Espacenet
US 11446398 B22022-09-203227P62330Espacenet
JP 2022524081 A2022-04-27106198P62330Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,492

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARF6 papersNewest fiscal year
ZIABC007365Regulation of ADP-ribosylation factor252025
R01DK064380Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and Ciliogenesis102025
R01HL016037Molecular Regulation of Cardiovascular 7 TM Receptors82025
T32HL007576Training in Cardiovascular Research82025
P30CA068485Cancer Center Support Grant72025
P30DK058404Molecular and Cellular Basis for Digestive Diseases72025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology62025
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System62025
P30CA016672Cancer Center Support Grant52025
P30CA036727Buffett Cancer Center Support Grant52025

1 to 10 of 2,492Source NIH's project files

See all 2,492 nih grants

Papers3,632

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A founder population reveals genetic variation with major effect on serious mental illness.medRxiv202642818201PubTator, text miningPubMed
The miR167-ARF8 module integrates HSFA1-HSFA2 and RVE4/8-ERF53/54 transcriptional cascades to enhance plant thermotolerance.Plant Cell202642798235PubTator, text miningPubMed
A biophysical hypothesis for compartment-specific conformational states of the IQSEC2 intrinsically disordered protein.Biophys J202642706723PubTator, text miningPubMed
Membrane engagement by the HLA-A cytoplasmic tail regulates endocytosis and surface retention.Cell Rep202642690931PubTator, text miningPubMed
IQSEC2 and ARF1 are involved in the development of the dentate gyrus.Biochim Biophys Acta Gen Subj202642685987PubTator, text miningPubMed
Targeting ARF6-SUCNR1 Axis: Antisense Oligonucleotide Adjuvants for Neutrophil Immunometabolism.Int J Mol Sci202642589657PubTator, text miningPubMed
Macropinocytosis of Amyloid Precursor Protein Is Regulated by the Recruitment and Activity of Fe65, Arf6 and Rho GTPases.Cells202642587775PubTator, text miningPubMed
SNAI1 ablation alters integrin-mediated adhesion and endocytic fate.Cell Death Dis202642586969PubTator, text miningPubMed
The Potential Target Value of ADP-Ribosylation Factor 6 in Insulin Secretion Regulation and the Treatment of Metabolic Disorders.Metabolites202642506459PubTator, text miningPubMed
Transcriptomic profiling of an in vivo diffuse large B-cell lymphoma model reveals molecular programs underlying CNS dissemination.Ann Hematol202642380537PubTator, text miningPubMed

1 to 10 of 3,632

See all 3,632 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/382

GET https://conductscience.org/api/genes/v1/382/patents?page=2