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KLRC1: killer cell lectin like receptor C1

1 protein, 46 patents, 1 drug, 22 trials, 2,941 NIH grants and 7,039 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolKLRC1HGNC
Namekiller cell lectin like receptor C1HGNC
NCBI Gene ID3821NCBI Gene
HGNC IDHGNC:6374HGNC
EnsemblENSG00000134545NCBI Gene
AliasesCD159A, CD159a, NKG2, NKG2-A, NKG2-B, NKG2ANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P26715NKG2-A/NKG2-B type II integral membrane protein2335Ensembl, GeneID, HGNCUniProt

Patents 46

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026503988 A2026-02-0341P26715Espacenet
JP 2026004568 A2026-01-1450758P26715Espacenet
JP 2026004568 A2026-01-1450760P26715Espacenet
EP 4644421 A12025-11-0541P26715Espacenet
EP 4641202 A22025-10-29415P26715Espacenet
JP 2025529142 A2025-09-042313P26715Espacenet
US 12371689 B22025-07-292313P26715Espacenet
JP 2025092554 A2025-06-194P26715Espacenet
JP 2025081301 A2025-05-272P26715Espacenet
KR 1020250017231 A2025-02-04415P26715Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MONALIZUMABCHEMBL4297787NKG2-A/NKG2-B type II integral membrane protein inhibitorINHIBITORChEMBL

Trials 22

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07146230MONALIZUMABPHASE2ClinicalTrials.gov
NCT06892223MONALIZUMABPHASE2ClinicalTrials.gov
NCT06769126MONALIZUMABPHASE2ClinicalTrials.gov
NCT06152523MONALIZUMABPHASE2ClinicalTrials.gov
NCT05903092MONALIZUMABPHASE2ClinicalTrials.gov
NCT05221840MONALIZUMABPHASE3ClinicalTrials.gov
NCT05061550MONALIZUMABPHASE2ClinicalTrials.gov
NCT04590963MONALIZUMABPHASE32023-11-18ClinicalTrials.gov
NCT04333914MONALIZUMABPHASE2ClinicalTrials.gov
NCT04307329MONALIZUMABPHASE2ClinicalTrials.gov

NIH grants 2941

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA111412NK cells, their receptors and cancer therapy552,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies512,025NIH's project files
P30CA008748Cancer Center Support Grant472,025NIH's project files
P30CA016672Cancer Center Support Grant292,025NIH's project files
P51OD011132Emory National Primate Research Center262,025NIH's project files
T32AI007290Molecular and Cellular Immunobiology222,025NIH's project files
P30CA077598Cancer Center Support Grant212,025NIH's project files
P30CA016058Cancer Center Support Grant192,025NIH's project files
P30CA091842Cancer Center Support Grant182,025NIH's project files
P50CA171963Specialized Program of Research Excellence (SPORE) in Leukemia182,025NIH's project files

Papers 7039

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823801PubTator, text miningPubMed
42809069PubTator, text miningPubMed
42808109PubTator, text miningPubMed
42798504PubTator, text miningPubMed
42798230PubTator, text miningPubMed
42781928PubTator, text miningPubMed
42777043PubTator, text miningPubMed
42772447PubTator, text miningPubMed
42768025PubTator, text miningPubMed
42767769PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license