Gene · 3832
KIF11: kinesin family member 11
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KIF11: kinesin family member 11. Genes, record 3832. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3832
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P52732 | Kinesin-like protein KIF11 | 1,056 | 62 | Ensembl, GeneID, HGNC |
Source UniProt
Patents97
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 180 | P52732 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50815 | P52732 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1820 | P52732 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4509 | P52732 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1820 | P52732 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4509 | P52732 | Espacenet |
| JP 2025013347 A | 2025-01-24 | 41 | P52732 | Espacenet |
| US 12201675 B2 | 2025-01-21 | 41 | P52732 | Espacenet |
| JP 2025003953 A | 2025-01-14 | 41 | P52732 | Espacenet |
| KR 1020240162163 A | 2024-11-14 | 41 | P52732 | Espacenet |
1 to 10 of 97
See all 97 patentsDrugs4
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| AZD-4877 | CHEMBL1829433 | Kinesin-like protein 1 inhibitor | INHIBITOR | ChEMBL |
| FILANESIB | CHEMBL2347655 | Kinesin-like protein 1 inhibitor | INHIBITOR | ChEMBL |
| ISPINESIB | CHEMBL228814 | Kinesin-like protein 1 inhibitor | INHIBITOR | ChEMBL |
| LITRONESIB | CHEMBL2105661 | Kinesin-like protein 1 inhibitor | INHIBITOR | ChEMBL |
Trials30
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT02384083 | FILANESIB | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT02092922 | FILANESIB | PHASE2 | ClinicalTrials.gov | |
| NCT01989325 | FILANESIB | PHASE2 | ClinicalTrials.gov | |
| NCT01416389 | LITRONESIB | PHASE2 | 2017-12-04 | ClinicalTrials.gov |
| NCT01372540 | FILANESIB | PHASE1 | ClinicalTrials.gov | |
| NCT01248923 | FILANESIB | PHASE1 | ClinicalTrials.gov | |
| NCT01214655 | LITRONESIB | PHASE1 | 2019-05-13 | ClinicalTrials.gov |
| NCT01214642 | LITRONESIB | PHASE1 | 2018-08-06 | ClinicalTrials.gov |
| NCT01214629 | LITRONESIB | PHASE1 | 2018-08-06 | ClinicalTrials.gov |
| NCT01059643 | LITRONESIB | PHASE2 | 2017-12-04 | ClinicalTrials.gov |
1 to 10 of 30
See all 30 trialsNIH grants1,705
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KIF11 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 17 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| R35GM126930 | Molecular Analysis of Kinetochore Function | 9 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 8 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 7 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 6 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA069533 | OHSU Knight Cancer Institute | 5 | 2025 |
| T32CA119925 | Integrated Biological Systems Training in Oncology | 5 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
1 to 10 of 1,705Source NIH's project files
See all 1,705 nih grantsPapers3,579
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Congenital microcephaly and bilateral chorioretinal atrophy associated with a KIF11 nonsense variant. | Ophthalmic Genet | 2026 | 42779270 | PubTator, text mining | PubMed |
| Immune cell enrichment characteristics and related key genes in intrauterine adhesion: insights from RNA-sequencing analysis. | Syst Biol Reprod Med | 2026 | 42763899 | PubTator, text mining | PubMed |
| Divergent microtubule-organizing center strategies in mammalian gametogenesis. | Trends Open | 2026 | 42761981 | PubTator, text mining | PubMed |
| Successful Surgical Management of Bilateral Tractional Retinal Detachments in a Neonate With a KIF11 Mutation. | J Vitreoretin Dis | 2026 | 42756196 | PubTator, text mining | PubMed |
| Clinical and Multimodal Imaging Features of Familial Exudative Vitreoretinopathy: The Genetic and Phenotypic Spectrum. | Clin Ophthalmol | 2026 | 42751639 | PubTator, text mining | PubMed |
| Molecular docking and molecular dynamics investigation of novels thiazolopyrimidines binding to canonical and alternative allosteric sites of kinesin Eg5. | J Mol Model | 2026 | 42742834 | PubTator, text mining | PubMed |
| Identification of a metastasis-associated prognostic gene signature in osteosarcoma through integrated bioinformatics and functional analysis. | Mamm Genome | 2026 | 42681084 | PubTator, text mining | PubMed |
| Exploring the mechanism of Shengmai San in treating lung adenocarcinoma based on bioinformatics and molecular dynamics simulation. | Medicine (Baltimore) | 2026 | 42675738 | PubTator, text mining | PubMed |
| Multi-Omics and Molecular Simulation Identify KIF11 as a Candidate Direct Target of Resveratrol in Hepatocellular Carcinoma. | J Hepatocell Carcinoma | 2026 | 42670538 | PubTator, text mining | PubMed |
| Traffic Jams in the Brain: How Kinesin Dysfunction Shapes Neurodevelopmental Disorders. | Curr Issues Mol Biol | 2026 | 42651835 | PubTator, text mining | PubMed |
1 to 10 of 3,579
See all 3,579 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3832
GET https://conductscience.org/api/genes/v1/3832/patents?page=2