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Gene · 3832

KIF11: kinesin family member 11

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KIF11: kinesin family member 11. Genes, record 3832. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3832

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Gene

Symbol
KIF11
HGNC
Name
kinesin family member 11
HGNC
NCBI Gene ID
3832
NCBI Gene
HGNC ID
HGNC:6388
HGNC
Ensembl
ENSG00000138160
NCBI Gene
Aliases
EG5, Eg5, HKSP, KNSL1, MCLMR, TRIP5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P52732Kinesin-like protein KIF111,05662Ensembl, GeneID, HGNC

Source UniProt

Patents97

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19180P52732Espacenet
JP 2026004568 A2026-01-1450815P52732Espacenet
EP 4650780 A22025-11-191820P52732Espacenet
EP 4641202 A22025-10-294509P52732Espacenet
JP 2025517970 A2025-06-121820P52732Espacenet
KR 1020250017231 A2025-02-044509P52732Espacenet
JP 2025013347 A2025-01-2441P52732Espacenet
US 12201675 B22025-01-2141P52732Espacenet
JP 2025003953 A2025-01-1441P52732Espacenet
KR 1020240162163 A2024-11-1441P52732Espacenet

1 to 10 of 97

See all 97 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AZD-4877CHEMBL1829433Kinesin-like protein 1 inhibitorINHIBITORChEMBL
FILANESIBCHEMBL2347655Kinesin-like protein 1 inhibitorINHIBITORChEMBL
ISPINESIBCHEMBL228814Kinesin-like protein 1 inhibitorINHIBITORChEMBL
LITRONESIBCHEMBL2105661Kinesin-like protein 1 inhibitorINHIBITORChEMBL

Trials30

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02384083FILANESIBPHASE1/PHASE2ClinicalTrials.gov
NCT02092922FILANESIBPHASE2ClinicalTrials.gov
NCT01989325FILANESIBPHASE2ClinicalTrials.gov
NCT01416389LITRONESIBPHASE22017-12-04ClinicalTrials.gov
NCT01372540FILANESIBPHASE1ClinicalTrials.gov
NCT01248923FILANESIBPHASE1ClinicalTrials.gov
NCT01214655LITRONESIBPHASE12019-05-13ClinicalTrials.gov
NCT01214642LITRONESIBPHASE12018-08-06ClinicalTrials.gov
NCT01214629LITRONESIBPHASE12018-08-06ClinicalTrials.gov
NCT01059643LITRONESIBPHASE22017-12-04ClinicalTrials.gov

1 to 10 of 30

See all 30 trials

NIH grants1,705

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKIF11 papersNewest fiscal year
P30CA016672Cancer Center Support Grant172025
P30CA008748Cancer Center Support Grant132025
R35GM126930Molecular Analysis of Kinetochore Function92025
P30CA015704Cancer Center Support Grant82025
P50CA097186The Pacific Northwest Prostate Cancer SPORE72025
P30CA014520UW Comprehensive Cancer Center Support62025
P30CA013148Comprehensive Cancer Center Support Grant52025
P30CA069533OHSU Knight Cancer Institute52025
T32CA119925Integrated Biological Systems Training in Oncology52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025

1 to 10 of 1,705Source NIH's project files

See all 1,705 nih grants

Papers3,579

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Congenital microcephaly and bilateral chorioretinal atrophy associated with a KIF11 nonsense variant.Ophthalmic Genet202642779270PubTator, text miningPubMed
Immune cell enrichment characteristics and related key genes in intrauterine adhesion: insights from RNA-sequencing analysis.Syst Biol Reprod Med202642763899PubTator, text miningPubMed
Divergent microtubule-organizing center strategies in mammalian gametogenesis.Trends Open202642761981PubTator, text miningPubMed
Successful Surgical Management of Bilateral Tractional Retinal Detachments in a Neonate With a KIF11 Mutation.J Vitreoretin Dis202642756196PubTator, text miningPubMed
Clinical and Multimodal Imaging Features of Familial Exudative Vitreoretinopathy: The Genetic and Phenotypic Spectrum.Clin Ophthalmol202642751639PubTator, text miningPubMed
Molecular docking and molecular dynamics investigation of novels thiazolopyrimidines binding to canonical and alternative allosteric sites of kinesin Eg5.J Mol Model202642742834PubTator, text miningPubMed
Identification of a metastasis-associated prognostic gene signature in osteosarcoma through integrated bioinformatics and functional analysis.Mamm Genome202642681084PubTator, text miningPubMed
Exploring the mechanism of Shengmai San in treating lung adenocarcinoma based on bioinformatics and molecular dynamics simulation.Medicine (Baltimore)202642675738PubTator, text miningPubMed
Multi-Omics and Molecular Simulation Identify KIF11 as a Candidate Direct Target of Resveratrol in Hepatocellular Carcinoma.J Hepatocell Carcinoma202642670538PubTator, text miningPubMed
Traffic Jams in the Brain: How Kinesin Dysfunction Shapes Neurodevelopmental Disorders.Curr Issues Mol Biol202642651835PubTator, text miningPubMed

1 to 10 of 3,579

See all 3,579 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3832

GET https://conductscience.org/api/genes/v1/3832/patents?page=2