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Gene · 3837

KPNB1: karyopherin subunit beta 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KPNB1: karyopherin subunit beta 1. Genes, record 3837. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3837

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Gene

Symbol
KPNB1
HGNC
Name
karyopherin subunit beta 1
HGNC
NCBI Gene ID
3837
NCBI Gene
HGNC ID
HGNC:6400
HGNC
Ensembl
ENSG00000108424
NCBI Gene
Aliases
IMB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14974Importin subunit beta-187623Ensembl, GeneID, HGNC

Source UniProt

Patents77

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450583Q14974Espacenet
EP 4649089 A12025-11-191Q14974Espacenet
EP 4650780 A22025-11-193413Q14974Espacenet
JP 2025517970 A2025-06-123413Q14974Espacenet
EP 4477266 A22024-12-181Q14974Espacenet
JP 2024520414 A2024-05-244Q14974Espacenet
US 11694765 B22023-07-04244Q14974Espacenet
US 11446398 B22022-09-2042556Q14974Espacenet
JP 2022524081 A2022-04-27145527Q14974Espacenet
JP 2020072653 A2020-05-14336Q14974Espacenet

1 to 10 of 77

See all 77 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants955

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKPNB1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control42025
P30AI027763UCSF-Bay Area Center for AIDS Research32025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
R35GM133552Coordination of chaperone interactions that dictate protein folding and trafficking32025
K12HD000850Pediatric Scientist Development Program22025
K12HD052896Child Health Research Career Development Award (CHRCDA) Program (K12)22025
P30AG072931Michigan Alzheimer's Disease Research Center22025

1 to 10 of 955Source NIH's project files

See all 955 nih grants

Papers1,340

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A novel minimally invasive diagnostic approach of various brain malignancies based on differential miRNA expression.J Neurooncol202642809056PubTator, text miningPubMed
Nuclear Import of E2F1 Regulated by KPNB1 is Essential for Proliferation and Invasion of Cervical Cancer Cells.Appl Biochem Biotechnol202642758397PubTator, text miningPubMed
Repurposing simeprevir uncovers a druggable KPNB1-p65-BCL2 survival axis in cancer.Cell Chem Biol202642537643PubTator, text miningPubMed
Artificial intelligence and multi-omics revealed the authentic regulation of ADP-ribosylation in modulation Treg/Th17 ecosystem and multi-target therapeutic strategy enrichment for HBV+ Hepatocellular Carcinoma patients.
Discov Oncol202642371264PubTator, text miningPubMed
Multi-omics analysis identifies a major histocompatibility complex class II-associated antigen-presenting cancer-associated fibroblast-like state linked to the nuclear factor erythroid 2-related factor 2-karyopherin subunit beta 1 axis in nonsmall cell lung cancer.
J Cell Commun Signal202642256528PubTator, text miningPubMed
Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance.Cell Rep202642176271PubTator, text miningPubMed
The competition between splicing and 3' processing shapes the human transcriptome.Genes Dev202642140670PubTator, text miningPubMed
PCSK9 as a Biomarker and Therapeutic Target for Anthracycline Cardiotoxicity Prevention: Recent Advancements and Future Perspectives.Cardiol Rev202642101949PubTator, text miningPubMed
TMEM106B C-terminal fragments drive nucleocytoplasmic transport failure and TDP-43 mislocalization in the aging human brain.bioRxiv202642094412PubTator, text miningPubMed
Prognostic value and cellular function of hsa_circ_0001588 in breast cancer.Cytotechnology202641953107PubTator, text miningPubMed

1 to 10 of 1,340

See all 1,340 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3837

GET https://conductscience.org/api/genes/v1/3837/patents?page=2