Gene · 3837
KPNB1: karyopherin subunit beta 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KPNB1: karyopherin subunit beta 1. Genes, record 3837. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3837
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14974 | Importin subunit beta-1 | 876 | 23 | Ensembl, GeneID, HGNC |
Source UniProt
Patents77
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 50583 | Q14974 | Espacenet |
| EP 4649089 A1 | 2025-11-19 | 1 | Q14974 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3413 | Q14974 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3413 | Q14974 | Espacenet |
| EP 4477266 A2 | 2024-12-18 | 1 | Q14974 | Espacenet |
| JP 2024520414 A | 2024-05-24 | 4 | Q14974 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 244 | Q14974 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 42556 | Q14974 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 145527 | Q14974 | Espacenet |
| JP 2020072653 A | 2020-05-14 | 336 | Q14974 | Espacenet |
1 to 10 of 77
See all 77 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants955
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KPNB1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 4 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 3 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 3 | 2025 |
| R35GM133552 | Coordination of chaperone interactions that dictate protein folding and trafficking | 3 | 2025 |
| K12HD000850 | Pediatric Scientist Development Program | 2 | 2025 |
| K12HD052896 | Child Health Research Career Development Award (CHRCDA) Program (K12) | 2 | 2025 |
| P30AG072931 | Michigan Alzheimer's Disease Research Center | 2 | 2025 |
1 to 10 of 955Source NIH's project files
See all 955 nih grantsPapers1,340
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A novel minimally invasive diagnostic approach of various brain malignancies based on differential miRNA expression. | J Neurooncol | 2026 | 42809056 | PubTator, text mining | PubMed |
| Nuclear Import of E2F1 Regulated by KPNB1 is Essential for Proliferation and Invasion of Cervical Cancer Cells. | Appl Biochem Biotechnol | 2026 | 42758397 | PubTator, text mining | PubMed |
| Repurposing simeprevir uncovers a druggable KPNB1-p65-BCL2 survival axis in cancer. | Cell Chem Biol | 2026 | 42537643 | PubTator, text mining | PubMed |
Artificial intelligence and multi-omics revealed the authentic regulation of ADP-ribosylation in modulation Treg/Th17 ecosystem and multi-target therapeutic strategy enrichment for HBV+ Hepatocellular Carcinoma patients. | Discov Oncol | 2026 | 42371264 | PubTator, text mining | PubMed |
Multi-omics analysis identifies a major histocompatibility complex class II-associated antigen-presenting cancer-associated fibroblast-like state linked to the nuclear factor erythroid 2-related factor 2-karyopherin subunit beta 1 axis in nonsmall cell lung cancer. | J Cell Commun Signal | 2026 | 42256528 | PubTator, text mining | PubMed |
| Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance. | Cell Rep | 2026 | 42176271 | PubTator, text mining | PubMed |
| The competition between splicing and 3' processing shapes the human transcriptome. | Genes Dev | 2026 | 42140670 | PubTator, text mining | PubMed |
| PCSK9 as a Biomarker and Therapeutic Target for Anthracycline Cardiotoxicity Prevention: Recent Advancements and Future Perspectives. | Cardiol Rev | 2026 | 42101949 | PubTator, text mining | PubMed |
| TMEM106B C-terminal fragments drive nucleocytoplasmic transport failure and TDP-43 mislocalization in the aging human brain. | bioRxiv | 2026 | 42094412 | PubTator, text mining | PubMed |
| Prognostic value and cellular function of hsa_circ_0001588 in breast cancer. | Cytotechnology | 2026 | 41953107 | PubTator, text mining | PubMed |
1 to 10 of 1,340
See all 1,340 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3837
GET https://conductscience.org/api/genes/v1/3837/patents?page=2